Skip to main content

Ceftezole

ADVERTISEMENT
Identification
Molecular formula
C9H8N4O3
CAS number
37364-32-7
IUPAC name
2-oxo-2-[3-(2H-tetrazol-5-yl)anilino]acetic acid
State
State

At room temperature, Ceftezole is found in a solid state, manifesting as a crystalline powder.

Melting point (Celsius)
206.00
Melting point (Kelvin)
479.00
Boiling point (Celsius)
570.00
Boiling point (Kelvin)
843.00
General information
Molecular weight
285.26g/mol
Molar mass
285.2460g/mol
Density
1.6720g/cm3
Appearence

Ceftezole is typically a lightweight, crystalline powder that is characterized by its usually white or off-white color.

Comment on solubility

Solubility of 2-oxo-2-[3-(2H-tetrazol-5-yl)anilino]acetic acid

The solubility of 2-oxo-2-[3-(2H-tetrazol-5-yl)anilino]acetic acid (C9H8N4O3) is influenced by its unique molecular structure, which contains both acidic and nitrogen-rich components. This compound demonstrates moderate solubility in aqueous solutions, particularly under certain pH conditions. The presence of the carboxylic acid group (-COOH) contributes significantly to its solubility profile.

Factors Affecting Solubility:

  • Polarity: The polar nature of the carboxylic functional group enhances interaction with water molecules.
  • pH Dependency: Solubility may increase in more alkaline conditions where the carboxylic acid can deprotonate.
  • Hydrogen Bonding: The potential for hydrogen bonding with water plays a crucial role in solubility.

Studies suggest that "like dissolves like," implying that the compound is more soluble in polar solvents than in non-polar solvents. While detailed solubility data may be limited, it is clear that conditions like temperature and solvent choice can significantly impact the effective solubility of 2-oxo-2-[3-(2H-tetrazol-5-yl)anilino]acetic acid.

In conclusion, understanding the solubility of this compound is vital for its applications in both pharmaceutical and chemical processes, showcasing its intricate balance between structure and solubility behavior.

Interesting facts

Interesting Facts About 2-oxo-2-[3-(2H-tetrazol-5-yl)anilino]acetic acid

2-oxo-2-[3-(2H-tetrazol-5-yl)anilino]acetic acid is a fascinating compound that merges the complexities of organic chemistry with practical applications in medicinal chemistry. Here are some captivating points regarding this compound:

  • Structural Highlights: This compound features a unique 2H-tetrazole ring, which is known for its ability to form hydrogen bonds, enhancing molecular interactions.
  • Biological Relevance: Compounds containing tetrazole rings, including this one, are often studied for their potential biological activities, including anti-inflammatory and analgesic properties.
  • Synthesis Insight: The synthesis of 2-oxo-2-[3-(2H-tetrazol-5-yl)anilino]acetic acid can involve multiple steps, showcasing the ingenuity of synthetic organic chemistry and its applications in designing new pharmaceuticals.
  • Drug Development: The versatility of this compound makes it a candidate for further exploration in drug development settings, as researchers can modify its structure to enhance effectiveness and reduce side effects.

In summary, 2-oxo-2-[3-(2H-tetrazol-5-yl)anilino]acetic acid serves as an exemplary model of how chemists can harness intricate molecular structures for innovative applications. As one famous chemist once said, "The beauty of chemistry lies in its ability to create the unexpected from the expected."

For students and professionals alike, understanding such compounds is not only crucial for advancing knowledge in the field but also for inspiring future innovations.

Synonyms
Acitazanolast
114607-46-4
MTCC
Acitazanolast [INN]
CCRIS 7505
Oxo-((3-(1H-tetrazol-5-yl)phenyl)amino)acetic acid
WP 871
3'-(1H-Tetrazol-5-yl)oxanilic acid
UNII-99Y8VJ356G
3'-(1H-Tetrazol-5-yl)oxanilic acid monohydrate
Oxanilic acid, 3-(1H-tetrazol-5-yl)-
DTXSID3048732
99Y8VJ356G
N-(3-(1H-Tetrazol-5-yl)phenyl)oxamic acid
2-((3-(1H-Tetrazol-5-yl)phenyl)-amino)-2-oxoacetic acid
Acetic acid, 2-oxo-2-[[3-(2H-tetrazol-5-yl)phenyl]amino]-
2-oxo-2-[3-(2H-tetrazol-5-yl)anilino]acetic acid
ACITAZANOLAST [MART.]
ACITAZANOLAST [WHO-DD]
DTXCID6028658
Acitazanolast (WP-871,Zepelin)
3-(1H-tetrazol-5-yl)Oxanilic Acid
Acetic acid, oxo-((3-(1H-tetrazol-5-yl)phenyl)amino)-
ACITAZANOLAST (MART.)
Acetic acid, oxo[[3-(1H-tetrazol-5-yl)phenyl]amino]-
2-((3-(1H-tetrazol-5-yl)phenyl)amino)-2-oxoacetic acid
Acetic acid,2-oxo-2-[[3-(2H-tetrazol-5-yl)phenyl]amino]-
WP-871
CAS-114607-46-4
Acetic acid, oxo((3-(1H-tetrazol-5-yl)phenyl)amino)-
acitazanolastum
MLS006011675
SCHEMBL342549
2-(3-(1H-tetrazol-5-yl)phenylamino)-2-oxoacetic acid
CHEMBL2104654
CHEBI:134948
VWQZJJZGISNFOE-UHFFFAOYSA-N
GLXC-04998
BCP26334
Tox21_113173
AKOS015914056
AKOS032947300
Tox21_113173_1
BCP9000228
NCGC00188429-02
DA-60769
HY-13218
MS-23339
SMR004094826
CS-0003181
NS00126166
G92035
SBI-0653901.0001
Zepenolast;MTCC; WP-871; WP 871; WP871
SR-01000944697
Oxo[[3-(1H-tetrazol-5-yl)phenyl]amino]acetic acid
SR-01000944697-1
BRD-K74236708-001-01-9
BRD-K74236708-001-02-7
Q27272251
F2119-0003