α-Ketoglutaric acid

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Identification

Molecular formula
C5H6O5
CAS Number
328-50-7
IUPAC Name
2-oxopentanedioic acid
Molecular Weight
146.11g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.5230g/cm3
Synonyms
2-ketoglutaric acid
Interesting facts

Interesting Facts About 2-Oxopentanedioic Acid

2-Oxopentanedioic acid, commonly known as oxaloacetic acid, is a fascinating compound that plays a crucial role in various biological processes. Here are some intriguing aspects of this compound:

  • Cyclic Metabolism: This compound is a key intermediate in the citric acid cycle (Krebs cycle), which is essential for cellular respiration in all aerobic organisms. Its presence helps facilitate the conversion of carbohydrates, fats, and proteins into energy.
  • Precursor to Amino Acids: 2-oxopentanedioic acid serves as a precursor for the synthesis of important amino acids, such as aspartate and asparagine, highlighting its importance in the metabolic pathways of living organisms.
  • Role in Plant Metabolism: The compound is also involved in the metabolism of plants, assisting in the synthesis of specific compounds that are significant for growth and development.
  • Clinical Implications: Due to its involvement in various metabolic pathways, studying 2-oxopentanedioic acid can provide insights into certain metabolic disorders and how they may be treated or managed.
  • Research Applications: This compound is often utilized in biochemical research to understand metabolic functions better and to develop pharmaceuticals targeting metabolic pathways.

In summary, 2-oxopentanedioic acid is not just a simple organic compound; it is a vital player in the complex web of biological processes that sustain life. Its contributions to metabolism and potential implications in health and disease make it an exhilarating topic of study for chemists and biologists alike. As we continue to explore its functions, the insights gained could be pivotal in advancing our understanding of metabolism and therapeutic strategies.

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