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2-(p-Tolyl)ethyl nicotinate

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Identification
Molecular formula
C15H15NO2
CAS number
4651-53-6
IUPAC name
2-(p-tolyl)ethyl pyridine-3-carboxylate
State
State

At room temperature, 2-(p-Tolyl)ethyl pyridine-3-carboxylate is in a solid state. It can easily be ground into a fine powder or used in its crystalline form for various chemical applications.

Melting point (Celsius)
50.00
Melting point (Kelvin)
323.15
Boiling point (Celsius)
333.00
Boiling point (Kelvin)
606.15
General information
Molecular weight
227.29g/mol
Molar mass
227.2710g/mol
Density
1.1000g/cm3
Appearence

2-(p-Tolyl)ethyl pyridine-3-carboxylate is typically a crystalline solid that can appear white to off-white in color. The crystalline nature often reflects light, giving it a slight sheen.

Comment on solubility

Solubility of 2-(p-tolyl)ethyl pyridine-3-carboxylate

2-(p-tolyl)ethyl pyridine-3-carboxylate is a complex organic compound whose solubility can be influenced by several factors. The key aspects to consider include:

  • Polarity: The presence of both an aromatic group (p-tolyl) and a carboxylate functional group plays a crucial role in determining solubility in various solvents. As a general rule, compounds that are polar tend to be more soluble in polar solvents such as water.
  • Functional Groups: The carboxylate group may increase solubility due to its ability to form hydrogen bonds with water, although the bulky p-tolyl group could hinder this effect.
  • Solvent Effects: In more nonpolar solvents like hexane or toluene, this compound might exhibit lower solubility compared to polar solvents. Thus, solvent choice is paramount.
  • Temperature: The solubility can also be temperature-dependent, with higher temperatures often enhancing the solubility of organic compounds.

Overall, it can be stated that 2-(p-tolyl)ethyl pyridine-3-carboxylate may demonstrate moderate solubility in polar solvents while exhibiting reduced solubility in nonpolar environments. Consequently, for practical applications, it is essential to consider the intended solvent when working with this compound to achieve optimal solubility.

Interesting facts

Interesting Facts about 2-(p-tolyl)ethyl pyridine-3-carboxylate

2-(p-tolyl)ethyl pyridine-3-carboxylate is a fascinating compound with several notable features that make it a subject of interest in organic chemistry. This compound can be appreciated for both its structural uniqueness and its potential applications. Here are some key points:

  • Versatile Synthetic Intermediates: This compound is considered an essential intermediate in the synthesis of various agrochemicals and pharmaceuticals, demonstrating its utility in organic synthesis.
  • Influence on Biological Activity: The presence of the pyridine moiety has been linked to various biological activities. Pyridine derivatives often exhibit antibacterial, antifungal, and anti-inflammatory properties.
  • Coordination Chemistry: Due to its nitrogen-containing structure, 2-(p-tolyl)ethyl pyridine-3-carboxylate can coordinate with transition metals, making it useful in the development of metal-organic frameworks and catalysts.
  • Research Applications: Researchers continue to explore the reactivity and properties of this compound, aiming to discover new derivatives with enhanced activity and novel properties.

In the words of a well-known chemist, “Chemistry is about taking the elements of nature and putting them in ways that reveal their hidden qualities.” 2-(p-tolyl)ethyl pyridine-3-carboxylate exemplifies this idea by showcasing how the arrangement of atoms can lead to significant biological and chemical properties.

The study of this compound not only highlights the relevance of organic compounds in our daily lives but also emphasizes the continuous exploration within the realm of chemistry, where each new derivative holds the potential to unlock further scientific discoveries.

Synonyms
p-Tolylmethylcarbinol-nicotinic acid ester
V94EB48QDC
2-(p-Tolyl)ethyl nicotinate
NICOTINIC ACID, p-METHYLPHENETHYL ESTER
21173-27-3
3-Pyridinecarboxylic acid, 2-(4-methylphenyl)ethyl ester
14008-88-9
BRN 0400509
RefChem:1061960
UNII-V94EB48QDC
DTXSID30175412
5-22-03-00343 (Beilstein Handbook Reference)