N-(p-tolylmethoxy)carbamimidamide | Solubility of Things

Identification

Molecular formula

C₉H₁₃N₃O

CAS number

138367-90-1

IUPAC name

2-(p-tolylmethoxy)guanidine

State

At room temperature, N-(p-tolylmethoxy)carbamimidamide is typically a crystalline solid.

Melting point (Celsius)

131.00

Melting point (Kelvin)

404.15

Boiling point (Celsius)

322.50

Boiling point (Kelvin)

595.65

General information

Molecular weight

179.22g/mol

Molar mass

179.2300g/mol

Density

1.1500g/cm³

Appearence

The appearance of N-(p-tolylmethoxy)carbamimidamide can vary depending on its form, but it is typically found as an off-white to pale yellow crystalline solid.

Comment on solubility

Solubility of 2-(p-tolylmethoxy)guanidine

The solubility of 2-(p-tolylmethoxy)guanidine can be an interesting consideration for its applications and behavior in different environments. Generally, the solubility of a compound depends on several factors, including:

Polarity: Due to its methoxy group, 2-(p-tolylmethoxy)guanidine is expected to exhibit polar characteristics, which often enhances its solubility in polar solvents such as water and alcohols.
Hydrogen Bonding: The presence of nitrogen atoms in the guanidine group may allow for hydrogen bonding with solvent molecules, further aiding solubility.
Temperature: As is common with many compounds, increasing temperature can improve solubility. This behavior might be leveraged when considering dissolution in practical applications.
pH Influence: The solubility of guanidine derivatives is often pH-dependent; in acidic or basic solutions, ionization can enhance solubility.

In summary, it's crucial to consider these factors when investigating the solubility of 2-(p-tolylmethoxy)guanidine. As with many chemical compounds, the interaction with solvents is key, and understanding this can lead to optimized uses in various chemical processes.

Interesting facts

Interesting Facts about 2-(p-tolylmethoxy)guanidine

2-(p-tolylmethoxy)guanidine is a fascinating compound with a variety of applications and significant chemical properties. Here are some interesting facts:

Versatility in Research: This compound is often used in biochemical research due to its ability to influence various biological pathways. Its unique structure allows it to interact with biological systems, making it a useful tool for drug design.
Structure-Inspired Design: The incorporation of the p-tolylmethoxy group enhances the lipophilicity of the guanidine moiety. This modification can lead to improved absorption and distribution properties, which are critical in pharmaceutical formulations.
Potential Therapeutic Applications: Recent studies have suggested that guanidine derivatives can exhibit anti-inflammatory and analgesic properties. This positions 2-(p-tolylmethoxy)guanidine as a promising candidate in pain management therapies.
Mechanistic Insights: Investigating the mechanism of action of this compound can provide valuable insights into its interactions at the molecular level. Understanding these interactions may lead to the development of more targeted therapies.
Environmental Considerations: In chemical synthesis, it's important to consider the environmental impact of compounds like 2-(p-tolylmethoxy)guanidine. Sustainable practices in its production could enhance its profile in green chemistry.

As a student of chemistry, exploring compounds such as 2-(p-tolylmethoxy)guanidine can lead to a deeper appreciation for the intricate relationships between molecular structure and function. In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This compound is a testament to that philosophy, opening doors to innovative research and potential breakthroughs in medicinal chemistry.