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Xylometazoline

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Identification
Molecular formula
C12H16N2
CAS number
526-36-3
IUPAC name
2-(p-tolylmethyl)-4,5-dihydro-1H-imidazole
State
State

Solid at room temperature. It is commonly supplied as its salt form, primarily hydrochloride.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
430.00
Boiling point (Kelvin)
703.15
General information
Molecular weight
200.29g/mol
Molar mass
200.2850g/mol
Density
1.0111g/cm3
Appearence

Xylometazoline is typically found as its hydrochloride salt, which is a white to slightly yellow crystalline powder.

Comment on solubility

Solubility of 2-(p-tolylmethyl)-4,5-dihydro-1H-imidazole

The solubility of 2-(p-tolylmethyl)-4,5-dihydro-1H-imidazole presents some intriguing characteristics that are essential to consider for various applications. While specific solubility values may vary, several general observations can be made:

  • Polar Nature: The imidazole ring contributes to potential interactions with polar solvents, suggesting moderate solubility in water due to its nitrogen atoms.
  • Organic Solvents: This compound is likely more soluble in organic solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO), which can effectively solvate the aromatic groups.
  • Temperature Effects: Solubility may increase with temperature, a common trend for many organic compounds, facilitating dissolution in various media during reactions or formulations.

To summarize, the solubility of 2-(p-tolylmethyl)-4,5-dihydro-1H-imidazole is influenced by its molecular structure and environmental conditions. As stated in chemical principles, “like dissolves like,” making this compound's behavior predictable in various solvent systems, warranting consideration in practical applications.

Interesting facts

Interesting Facts About 2-(p-tolylmethyl)-4,5-dihydro-1H-imidazole

2-(p-tolylmethyl)-4,5-dihydro-1H-imidazole is a fascinating compound that falls under the category of heterocycles due to its unique ring structure. Here are some compelling facts that make this compound noteworthy:

  • Heterocyclic Chemistry: As a member of the imidazole family, this compound exhibits a five-membered aromatic ring containing both nitrogen and carbon atoms, contributing to its unique chemical reactivity and properties.
  • Biological Significance: Compounds containing imidazole rings are often found in biological systems. They can play essential roles in enzymatic reactions and are components of various *biologically active* molecules, such as histidine, which is vital for protein synthesis.
  • Drug Development: Chemical derivatives of imidazole are widely investigated in pharmaceutical research. For instance, certain imidazole compounds exhibit *antifungal* and *antimicrobial* properties, showing potential in developing therapeutic agents.
  • Substituent Effects: The presence of the *p-tolylmethyl* group can significantly influence the compound's chemical behavior, affecting its *solubility*, *reactivity*, and interaction with other molecules. Such substituents can modulate biological activity and improve pharmacokinetic properties.
  • Research Applications: Researchers are investigating the multifunctional properties of imidazole-based compounds, leading to advancements in drug discovery, agrochemicals, and material sciences. The versatility of this compound offers exciting opportunities for innovative applications.

Overall, 2-(p-tolylmethyl)-4,5-dihydro-1H-imidazole exemplifies the intriguing intersection of organic chemistry and its practical applications in various fields. As we explore more about this compound, we deepen our understanding of heterocyclic chemistry and its significance in the natural and synthetic world.

Synonyms
2-(p-Methylbenzyl)-2-imidazoline
3038-62-8
2-IMIDAZOLINE, 2-(p-METHYLBENZYL)-
BRN 0005855
2-(4'-Methylbenzyl)imidazolin
2-(4'-Methylbenzyl)imidazolin [German]
DTXSID50184465
DTXCID60106956
5-23-07-00012 (beilstein handbook reference)
CHEMBL301859
2- (4'-Methyl-benzyl)-imidazolin