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2-pentylbenzimidazole

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Identification
Molecular formula
C12H14N2
CAS number
29583-89-1
IUPAC name
2-pentyl-1H-benzimidazole
State
State

At room temperature, 2-pentylbenzimidazole is typically a solid, although it might also appear as a viscous liquid depending on purity and conditions.

Melting point (Celsius)
74.00
Melting point (Kelvin)
347.15
Boiling point (Celsius)
327.00
Boiling point (Kelvin)
600.15
General information
Molecular weight
188.27g/mol
Molar mass
188.2670g/mol
Density
1.0600g/cm3
Appearence

2-Pentylbenzimidazole generally appears as a clear to pale yellow liquid or sometimes as a crystalline solid. It may have a slight aromatic odor, characteristic of benzimidazole derivatives. The substance is considerably stable but should be handled with care as benzimidazoles can be sensitive to air and light.

Comment on solubility

Solubility of 2-pentyl-1H-benzimidazole

2-pentyl-1H-benzimidazole is a compound that exhibits interesting solubility characteristics, largely influenced by its structural features. Generally, the solubility of such organic compounds can vary significantly based on a few key parameters:

  • Polarity: The presence of non-polar alkyl chains in 2-pentyl-1H-benzimidazole allows it to be more soluble in non-polar solvents.
  • Functional Groups: The benzimidazole moiety can influence solubility in polar solvents to some extent, due to potential hydrogen bonding. However, the hydrophobic nature of the pentyl group typically dominates.
  • Temperature: As with many organic compounds, increased temperature may enhance solubility by promoting better molecular motion and interaction with solvents.

In general, **2-pentyl-1H-benzimidazole is expected to exhibit limited solubility in water** due to its relatively hydrophobic character. Instead, it may demonstrate better solubility in organic solvents such as:

  • Hexane
  • Toluene
  • Chloroform

As a compound with a balance between hydrophobic and polar features, its solubility profile makes it particularly interesting for applications where selective solubility is advantageous. As one might say, “The solubility of compounds is often a dance between the polar and non-polar elements at play.”

Interesting facts

Interesting Facts About 2-Pentyl-1H-benzimidazole

2-Pentyl-1H-benzimidazole is a fascinating chemical compound that combines elements of both benzene and imidazole rings. Here are some interesting insights about this compound:

  • Versatile Applications: This compound has shown potential in various fields, such as pharmaceuticals and materials science. Its unique structure allows it to function as a building block in drug design, particularly in the development of anti-cancer and antimicrobial agents.
  • Synthesis Techniques: 2-Pentyl-1H-benzimidazole can be synthesized through several methods, including the condensation of o-phenylenediamine with long-chain aldehydes. This synthetic versatility makes it an accessible compound for researchers.
  • Biological Activity: Researchers have studied this compound for its possible biological effects. For instance, it has been noted for its potential *antioxidant* and *anti-inflammatory* properties, which can have implications in therapeutic applications.
  • Structural Features: The presence of a pentyl group on the benzimidazole core adds a hydrophobic character, which can influence the compound's interactions in biological systems, enhancing its permeability and bioavailability.
  • Research Opportunities: Due to its intriguing properties, 2-pentyl-1H-benzimidazole continues to be a subject of scientific inquiry, offering numerous opportunities for further research in organic chemistry and medicinal chemistry.

In conclusion, 2-pentyl-1H-benzimidazole is more than just a chemical compound; it represents a convergence of chemistry and biology with the potential for innovative applications in a variety of fields. As research progresses, we may uncover even more fascinating aspects of this compound that could contribute to advancing our understanding of chemistry and its practical uses.

Synonyms
5851-46-7
2-Pentyl-1H-benzimidazole
2-pentyl-1H-benzo[d]imidazole
2-Pentylbenzimidazole
1H-Benzimidazole,2-pentyl-(9CI)
2-n-Amylbenzimidazole
2-pentyl-1H-1,3-benzodiazole
2-n-Pentylbenzimidazole
BENZIMIDAZOLE, 2-PENTYL-
1H-Benzimidazole, 2-pentyl-
CHEMBL155867
BRN 0128302
2-Amylbenzimidazole
MFCD00628961
5-23-07-00048 (Beilstein Handbook Reference)
2-Pentyl-1H-benzimidazole #
SCHEMBL170803
DTXSID20207231
HMS1607J11
ALBB-036494
FAA85146
BDBM50404854
STL356875
AKOS000635032
CCG-103331
DS-19281
CS-0152310
EN300-02936
AG-205/09848039
Z55692917
5856-41-7