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2-Pentyl-3,4-dihydroisoquinoline

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Identification
Molecular formula
C14H19N
CAS number
36171-85-0
IUPAC name
2-pentyl-3,4-dihydro-1H-isoquinoline
State
State

In its natural state at room temperature, 2-Pentyl-3,4-dihydroisoquinoline exists as a liquid. It is typically colorless to pale yellow and may have an amine-like odor.

Melting point (Celsius)
-12.00
Melting point (Kelvin)
261.15
Boiling point (Celsius)
312.00
Boiling point (Kelvin)
585.15
General information
Molecular weight
201.32g/mol
Molar mass
201.3170g/mol
Density
1.0036g/cm3
Appearence

2-Pentyl-3,4-dihydroisoquinoline is typically in a liquid form at room temperature. Its appearance can range from clear to slightly yellowish, depending on purity and specific conditions.

Comment on solubility

Solubility of 2-pentyl-3,4-dihydro-1H-isoquinoline

The solubility of 2-pentyl-3,4-dihydro-1H-isoquinoline presents intriguing characteristics due to its molecular structure. A few points to consider are:

  • Polarity: The compound has varying degrees of polarity, which can influence its solubility in different solvents.
  • Solvent Choice: It is generally expected to be more soluble in organic solvents than in polar solvents like water due to its hydrophobic aliphatic side chain.
  • Temperature Dependence: As with many organic compounds, the solubility might increase with temperature, enabling better dissolution in solvents as kinetic energy increases.
  • Hydrophobic Interactions: The pentyl group contributes to hydrophobic interactions, making solubility in polar media quite limited.

In summary, while 2-pentyl-3,4-dihydro-1H-isoquinoline may demonstrate moderate solubility in **non-polar organic solvents**, its solubility in polar solvents like water is likely very low. The understanding of solubility is essential for its potential applications in various chemical fields.

Interesting facts

Interesting Facts about 2-pentyl-3,4-dihydro-1H-isoquinoline

2-pentyl-3,4-dihydro-1H-isoquinoline is a fascinating compound with intriguing properties and applications in the field of chemistry. This compound belongs to a class of organic compounds known as isoquinolines, which are characterized by their structure combining a benzene ring and a heterocyclic ring containing nitrogen.

Structural Characteristics

  • Isoquinoline Backbone: Its structure includes a bicyclic system where the isoquinoline framework can significantly influence its reactivity and interactions with other molecules.
  • Substituted Pentyl Group: The presence of the pentyl side chain contributes to its solubility in organic solvents, making it versatile for various applications.

Applications and Significance

This compound has attracted attention in multiple areas:

  • Pharmaceutical Research: Isoquinolines have been studied for their biological activities, including potential therapeutic effects, particularly as analgesics, anti-inflammatory agents, and more.
  • Organic Synthesis: The unique structure of 2-pentyl-3,4-dihydro-1H-isoquinoline allows it to serve as a valuable intermediate in organic synthesis.

Biological Relevance

There's ongoing research into how derivatives of isoquinoline, like this compound, can interact with biological systems. Some isoquinolines are known to:

  • Exhibit antioxidant properties.
  • Act as enzyme inhibitors, which is crucial for drug discovery.
  • Demonstrate neuroprotective effects, making them candidates for treating neurodegenerative diseases.

Conclusion

In summary, 2-pentyl-3,4-dihydro-1H-isoquinoline embodies the complexity and utility of isoquinoline derivatives in both academic and practical contexts. As research progresses, its potential continues to intrigue scientists and chemists who explore the vast realm of organic compounds.

Synonyms
NIOSH/NX5112070
1,2,3,4-Tetrahydro-2-pentylisoquinoline
NX51120700
Isoquinoline, 1,2,3,4-tetrahydro-2-pentyl-
SCHEMBL589583
AKOS017160719