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Benzocaine

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Identification
Molecular formula
C9H11NO2
CAS number
94-09-7
IUPAC name
2-(pentylamino)ethyl 4-aminobenzoate
State
State

At room temperature, benzocaine is in the solid state. It is typically handled as a finely divided powder for use in various applications.

Melting point (Celsius)
88.00
Melting point (Kelvin)
361.00
Boiling point (Celsius)
310.30
Boiling point (Kelvin)
583.50
General information
Molecular weight
165.19g/mol
Molar mass
165.1890g/mol
Density
1.1700g/cm3
Appearence

Benzocaine appears as a white, odorless, crystalline powder. It is known for its slightly bitter taste and has a tendency to form needle-like crystals when recrystallized from organic solvents.

Comment on solubility

Solubility of 2-(pentylamino)ethyl 4-aminobenzoate

2-(pentylamino)ethyl 4-aminobenzoate, while its exact solubility characteristics may depend on various conditions, typically exhibits a few noteworthy aspects:

  • Polarity: The presence of amino groups suggests that this compound may have some polarity, which can enhance solubility in polar solvents such as water.
  • Hydrophobic Character: The pentyl group adds a degree of hydrophobicity, potentially leading to lower solubility in water compared to more polar compounds.
  • Solvent Compatibility: This compound is likely to be more soluble in organic solvents such as ethanol or acetone, due to the balance between its polar and non-polar characteristics.

In summary, while 2-(pentylamino)ethyl 4-aminobenzoate may show some solubility in water due to its amino functionalities, it is essential to consider factors such as temperature and pH, which can significantly influence its solubility behavior. As noted, "like dissolves like," meaning that the compound will generally exhibit greater solubility in non-polar solvents due to its hydrophobic characteristics.

Interesting facts

Interesting Facts About 2-(pentylamino)ethyl 4-aminobenzoate

2-(pentylamino)ethyl 4-aminobenzoate is a fascinating compound that belongs to a class of substances known for their diverse biological activities. This compound, often cited in pharmacological studies, displays potential therapeutic applications. Here are some compelling aspects of this compound:

  • Pharmaceutical Potential: It has been explored for its role as an intermediate in the synthesis of several pharmaceutical agents, making it a compound of interest in drug discovery.
  • Structure-Activity Relationship: The various functional groups present in its structure allow scientists to study its interaction with biological targets, leading to insights into how structural modifications can enhance efficacy.
  • Analytical Chemistry: The detection and quantification of 2-(pentylamino)ethyl 4-aminobenzoate in biological samples can be accomplished using techniques like HPLC, demonstrating its importance in analytical chemistry.
  • Biological Studies: Research has suggested that this compound may exhibit effects on cellular mechanisms, opening up pathways for studies in areas such as cancer research and neuropharmacology.

In essence, 2-(pentylamino)ethyl 4-aminobenzoate is more than just a chemical entity; it is a crucial component in the ongoing journey of scientific exploration. As one researcher aptly put it, "Understanding the nuances of chemical interactions is key to unlocking the doors of modern medicine." By examining compounds like this, scientists continue to push the boundaries of what is possible in the realm of therapeutic development.

Synonyms
Naepaine
Amylsine
Amalcaine
Amylcain
Amylcaine
Naopaine
Amylsin
2188-67-2
Naepaine base
2-(pentylamino)ethyl 4-aminobenzoate
2-n-Amylaminoethyl p-aminobenzoate
2-n-Pentylaminoethyl p-aminobenzoate
NSC-41534
p-Aminobenzoic acid 2-n-amylaminoethyl ester
NAEPAINE [MI]
p-Aminobenzoic acid 2-n-pentylaminoethyl ester
2-(Pentylamino)ethanol 4-aminobenzoate (ester)
NSC 41534
J1Z219971C
BRN 2808234
BENZOIC ACID, p-AMINO-, 2-(PENTYLAMINO)ETHYL ESTER
UNII-J1Z219971C
DTXSID70176281
Ethanol, 2-(pentylamino)-, 4-aminobenzoate (ester)
Ethanol, 2-(pentylamino)-, p-aminobenzoate (ester)
3-14-00-01040 (Beilstein Handbook Reference)
DTXCID4098772
Ethanol, 2-(pentylamino)-, 4-aminobenzoate (ester) (9CI)
Ethanol, 2-(pentylamino)-, p-aminobenzoate (ester) (8CI)
Amylsin; Amylsine; NSC 41534; Naopaine
SCHEMBL24437
CHEMBL2110915
Ethanol, p-aminobenzoate (ester)
CHEBI:135021
Ethanol, 4-aminobenzoate (ester)
NSC41534
Benzoic acid, 2-(pentylamino)ethyl ester
p-Aminobenzoic acid 2-(n-amylamino)ethyl ester
p-Aminobenzoic acid 2-(n-pentylamino)ethyl ester
Q27281039