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Phenoxyethylamine

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Identification
Molecular formula
C8H11NO
CAS number
140-53-4
IUPAC name
2-phenoxyethanamine
State
State

At room temperature, phenoxyethylamine is in a liquid state. It is colorless or slightly yellow and is soluble in water and many organic solvents.

Melting point (Celsius)
-11.80
Melting point (Kelvin)
261.35
Boiling point (Celsius)
210.00
Boiling point (Kelvin)
483.15
General information
Molecular weight
137.18g/mol
Molar mass
137.1810g/mol
Density
1.0540g/cm3
Appearence

Phenoxyethylamine is typically a clear to pale yellow liquid. It has a distinct amine-like, somewhat floral odor. It is often used in chemical research and industrial applications.

Comment on solubility

Solubility of 2-phenoxyethanamine

2-phenoxyethanamine, with the molecular formula C8H11NO, demonstrates interesting solubility characteristics that can influence its applications in various chemical processes. Here are some key points regarding its solubility:

  • Polar Solvent Compatibility: 2-phenoxyethanamine is generally soluble in polar solvents such as water and alcohols, thanks to its amino group that can engage in hydrogen bonding.
  • Hydrophobic Interactions: The presence of the phenoxy group provides some hydrophobic characteristics, which may limit its solubility in purely non-polar solvents.
  • Solubility Variation: The solubility can vary significantly with changing temperature and the presence of other solutes or additives. Typically, increasing temperature can enhance its solubility in water.
  • pH Dependence: The solubility of 2-phenoxyethanamine may also be affected by the pH of the solution, as the amino group can protonate, affecting its overall charge and hence solubility behavior.

In summary, 2-phenoxyethanamine is a compound that exhibits notable solubility in polar environments, with factors like temperature, pH, and solvent choice playing crucial roles. As quoted, “Understanding the solubility is key to unlocking the potential of chemical compounds,” which rings true for this compound as well.

Interesting facts

Interesting Facts about 2-Phenoxyethanamine

2-Phenoxyethanamine is a fascinating compound that captures the interest of both researchers and students in the field of chemistry. Here are some intriguing aspects of this compound:

  • Chemical Structure: It is an aromatic amine, featuring a phenoxy group attached to an ethanamine backbone. This unique structure contributes to its diverse reactivity and solubility in organic solvents.
  • Applications: 2-Phenoxyethanamine is used in various industrial applications, including:
    • As a building block in synthesizing clinically relevant pharmaceuticals.
    • As an intermediate for the development of agrochemicals.
    • In polymer chemistry for creating specialty polymers.
  • Biological Significance: The amine functional group in this compound can interact with biological systems, making it of interest in medicinal chemistry.
  • Safety Considerations: As with all chemicals, researchers must handle 2-phenoxyethanamine with caution due to its potential toxicity. Proper safety protocols should be followed, including the use of personal protective equipment (PPE).
  • Research Potential: Ongoing studies are exploring its properties and potential therapeutic uses in treating various diseases, further emphasizing the importance of compound exploration in drug discovery.

In conclusion, 2-Phenoxyethanamine embodies the dynamic nature of chemistry, bridging the gap between synthetic techniques and practical applications. This compound not only serves as a crucial intermediary in chemical synthesis but also promises potential health benefits, keeping it a point of interest for scientists alike.

Synonyms
2-Phenoxyethylamine
2-phenoxyethanamine
Phenoxyethylamine
BRN 0774671
EINECS 217-153-6
UNII-8DGQ1B38R5
8DGQ1B38R5
DTXSID30170028
PHENETOLE, .BETA.-AMINO-
4-06-00-00663 (Beilstein Handbook Reference)
PHENETOLE, BETA-AMINO-
DTXCID7092519
imlaixazmvdrga-uhfffaoysa-n
inchi=1/c8h11no/c9-6-7-10-8-4-2-1-3-5-8/h1-5h,6-7,9h
1758-46-9
Ethanamine, 2-phenoxy-
2-PHENOXYLETHYLAMINE
ETHYLAMINE, 2-PHENOXY-
(2-phenoxyethyl)amine
2-phenoxyethan-1-amine
MFCD00052975
CHEMBL217680
(2-aminoethoxy)benzene
2-Phenoxy-ethylamine
alpha-Phenoxy-beta-aminoethane
1-Amino-2-phenoxyethane
2-phenoxyethylamino
2- phenoxyethylamine
2-phenoxyethyl amine
2-Phenoxy ethylamine
2-Phenoxyethyl-amine
P-Amino-ethoxybenzene
2-Phenoxyethylamine, 98%
SCHEMBL43067
C8H10NO
SCHEMBL9323817
HMS1788G02
.alpha.-Phenoxy-.beta.-aminoethane
ALBB-027086
BBL028054
BDBM50302307
STK711818
AKOS000112403
CS-W002257
GS-3384
NCGC00341075-01
AC-15743
SY004523
DB-021479
NS00025771
P1663
EN300-16223
AB00992856-01
AB00992856-03
Q27270226