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Desmethylperazine

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Identification
Molecular formula
C13H16N2
CAS number
5488-00-4
IUPAC name
2-phenyl-2-(1-piperidyl)acetonitrile
State
State

At room temperature, Desmethylperazine is typically found in a solid state. Its crystalline structure makes it stable and it is easy to handle in laboratory settings or for pharmaceutical applications.

Melting point (Celsius)
85.00
Melting point (Kelvin)
358.00
Boiling point (Celsius)
241.00
Boiling point (Kelvin)
514.00
General information
Molecular weight
198.28g/mol
Molar mass
198.2790g/mol
Density
1.0600g/cm3
Appearence

Desmethylperazine typically appears as a white or off-white crystalline solid. Its appearance may vary slightly depending on the specific form or preparation of the compound.

Comment on solubility

Solubility of 2-phenyl-2-(1-piperidyl)acetonitrile

2-phenyl-2-(1-piperidyl)acetonitrile is an intriguing compound that exhibits a relatively moderate solubility profile in various solvents. Its solubility characteristics are influenced by the following factors:

  • Polarity: The presence of the nitrile functional group contributes to its polar characteristics, enhancing solubility in polar solvents.
  • Solvation Interactions: In solvents like water, the formation of hydrogen bonds with surrounding molecules can play a role in its solubility.
  • Organic Solvents: This compound tends to be more soluble in organic solvents such as ethanol and methanol due to its hydrophobic phenyl ring.
  • Temperature Dependence: Generally, an increase in temperature can lead to an increased solubility of solids in liquids.

While precise solubility values may vary, it is crucial to note that "a compound's solubility is often a critical property for its application in various fields, including pharmaceuticals and material sciences." Understanding these solubility traits can significantly impact its utilization and effectiveness in different scenarios.

Interesting facts

Exploring 2-phenyl-2-(1-piperidyl)acetonitrile

2-phenyl-2-(1-piperidyl)acetonitrile, also known as a notable organic compound, holds significant interest in the field of medicinal chemistry. This compound is particularly recognized for its structure, which combines elements of aromaticity and cyclic organic chemistry, making it a fascinating subject of study.

Key Characteristics

  • Diverse Applications: Used in the synthesis of pharmaceutical intermediates, it serves as a precursor to various biologically active molecules.
  • Potential Therapeutic Uses: There’s ongoing research into its potential applications in treating neurodegenerative diseases and as an analgesic.
  • Unique Structure: The presence of a piperidine ring lends unique properties to the compound, affecting its interaction with biological receptors.

Moreover, 2-phenyl-2-(1-piperidyl)acetonitrile is an example of how subtle changes in chemical structure can lead to significant differences in chemical behavior. Researchers often quote, "The magic lies in the molecules whose arrangements change everything." This emphasizes the importance of understanding the nuances in organic synthesis.

The Scientific Impact

On a broader scale, studying compounds like 2-phenyl-2-(1-piperidyl)acetonitrile contributes to our understanding of pharmaceutical chemistry and molecular design, highlighting the intricate connection between structure and function.

In summary, this compound represents a fascinating avenue for scientific exploration, merging the knowledge of synthetic methods with practical applications in medicine and pharmacology. The continuing research into its properties promises to uncover new horizons in drug development and therapeutic strategies.

Synonyms
2-Phenyl-2-piperidinoacetonitrile
227-291-9
5766-79-0
USAF A-2217
2-phenyl-2-(piperidin-1-yl)acetonitrile
2-phenyl-2-piperidin-1-ylacetonitrile
ACETONITRILE, 2-PHENYL-2-PIPERIDINO-
NSC 15446
1-Piperidineacetonitrile, alpha-phenyl-
1-Piperidineacetonitrile, .alpha.-phenyl-
Phenylpiperidinoacetonitrile
2-phenyl-2-(1-piperidyl)acetonitrile
.alpha.-Tolunitrile-.alpha.-piperidino-
.alpha.-(1-Piperidyl)-.alpha.-tolunitrile
.alpha.-Phenyl-.alpha.-(1-piperidino)-acetonitril
alpha-Tolunitrile-alpha-piperidino-
alpha-Tolunitrile, alpha-piperidino-
EINECS 227-291-9
alpha-(1-Piperidyl)-alpha-tolunitrile
BRN 0168026
AI3-02750
NSC15446
MFCD00023711
alpha-Phenyl-alpha-(1-piperidino)-acetonitril [German]
Maybridge1_000058
alpha-Phenyl-alpha-(1-piperidino)-acetonitril
MixCom1_000102
WLN: T6NTJ AYR&CN
1-(1-Cyanobenzyl)piperidine
5-20-03-00071 (Beilstein Handbook Reference)
1-(a-Cyanobenzyl)-piperidine
SCHEMBL519228
Phenyl(1-piperidinyl)acetonitrile
DTXSID401299234
1-(.alpha.-Cyanobenzyl)-piperidine
Phenyl(1-piperidinyl)acetonitrile #
NSC-15446
XBX 00107
I+/--Phenyl-1-piperidineacetonitrile
AKOS000352080
AKOS022203961
CCG-237705
MB00327
CS-10072
DB-015437
CS-0326944
NS00046691
InChI=1/C13H16N2/c14-11-13(12-7-3-1-4-8-12)15-9-5-2-6-10-15/h1,3-4,7-8,13H,2,5-6,9-10H