Ioxaglic acid | Solubility of Things

Identification

Molecular formula

C₁₉H₁₆I₃NO₅

CAS number

31112-62-6

IUPAC name

2-phenyl-2-[2,4,6-triiodo-3-(2-oxo-1-piperidyl)phenoxy]acetic acid

State

At room temperature, ioxaglic acid is in a solid state and typically available as a crystalline powder.

Melting point (Celsius)

245.00

Melting point (Kelvin)

518.15

Boiling point (Celsius)

0.00

Boiling point (Kelvin)

0.00

General information

Molecular weight

821.02g/mol

Molar mass

821.0150g/mol

Density

2.1000g/cm³

Appearence

Ioxaglic acid appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-phenyl-2-[2,4,6-triiodo-3-(2-oxo-1-piperidyl)phenoxy]acetic acid

The solubility of 2-phenyl-2-[2,4,6-triiodo-3-(2-oxo-1-piperidyl)phenoxy]acetic acid is influenced by several factors given its complex structure. Here are some key points regarding its solubility:

Polarity: Due to the presence of multiple electronegative atoms, such as iodine and oxygen, the compound exhibits polar characteristics that may enhance its solubility in polar solvents.
Hydrogen Bonding: The presence of acidic functional groups suggests that this compound can participate in hydrogen bonding, which can further increase solubility in aqueous solutions.
Solvent Interactions: While it may be soluble in organic solvents like DMSO or ethanol, its solubility in water could be limited by hydrophobic phenyl groups.
Temperature Influence: Like many organic compounds, solubility may be enhanced at higher temperatures, so solubility testing at various temperatures could provide valuable insights.

In summary, while 2-phenyl-2-[2,4,6-triiodo-3-(2-oxo-1-piperidyl)phenoxy]acetic acid shows potential for solubility in various solvents, its complex structure suggests that experimental determination under specific conditions is essential for understanding its solubility profile.

Interesting facts

Interesting Facts about 2-phenyl-2-[2,4,6-triiodo-3-(2-oxo-1-piperidyl)phenoxy]acetic acid

2-phenyl-2-[2,4,6-triiodo-3-(2-oxo-1-piperidyl)phenoxy]acetic acid, a complex chemical compound, showcases intriguing characteristics due to its unique molecular structure. Here are some noteworthy points:

Pharmaceutical Potential: This compound is studied for its potential therapeutic applications, particularly in the realm of pharmacology. Its phenoxy and piperidyl functional groups may contribute to bioactivity, making it a candidate in drug design and development.
Triiodination: The presence of three iodine atoms significantly influences the compound's properties. Iodine substitution can enhance bioavailability and modify metabolic pathways, which might be beneficial in medicinal chemistry.
Structure-Activity Relationship (SAR): The intricate architecture of this compound allows scientists to explore its SAR, helping to understand how changes in chemical structure can affect biological activity. Such explorations are crucial for optimizing drug candidates.
Environmental Considerations: Iodinated compounds often raise environmental concerns due to the potential for bioaccumulation. As researchers work with this compound, they must also consider its ecological impact and pathways of degradation.
Research Directions: The unique characteristics of this compound open avenues for further research, such as its potential role in synthesizing advanced materials or as a biochemical probe in cellular studies.

In summary, 2-phenyl-2-[2,4,6-triiodo-3-(2-oxo-1-piperidyl)phenoxy]acetic acid stands as a fascinating subject of study, highlighting the intricate relationship between chemical structure and biological activity. As researchers delve deeper into its potential, we may uncover novel applications that extend beyond traditional medicinal use.