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Ioversol

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Identification
Molecular formula
C18H24I3N3O9
CAS number
87771-40-2
IUPAC name
2-phenyl-2-[2,4,6-triiodo-3-(2-oxomorpholin-4-yl)phenoxy]acetic acid
State
State

Ioversol is typically found in a solid state at room temperature. It is commonly used in a dissolved form as a contrast medium in medical imaging.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
807.11g/mol
Molar mass
807.1120g/mol
Density
1.4690g/cm3
Appearence

Ioversol appears as a white, crystalline powder. It is odorless and is characterized by its high iodine content, contributing to its use in radiographic imaging.

Comment on solubility

Solubility of 2-phenyl-2-[2,4,6-triiodo-3-(2-oxomorpholin-4-yl)phenoxy]acetic acid

The solubility of 2-phenyl-2-[2,4,6-triiodo-3-(2-oxomorpholin-4-yl)phenoxy]acetic acid can be quite intriguing due to its complex structure. This compound, featuring multiple aromatic rings and halogen substituents, tends to exhibit particular solubility behavior influenced by several factors:

  • Polarity: The presence of the oxomorpholine moiety can enhance the polarity of the molecule, potentially improving its solubility in polar solvents.
  • Hydrogen Bonding: With functional groups capable of forming hydrogen bonds, one might expect increased solubility in protic solvents such as water or alcohols.
  • Halogen Effect: The tri-iodo substituents may contribute to decreased solubility in non-polar solvents due to increased molecular weight and reduced overall reactivity.

Typically, compounds with extensive aromatic systems and halogen atoms exhibit reduced solubility in aqueous environments, whereas polar or protic solvents could facilitate dissolution. As a general observation, the solubility of this compound can vary significantly depending on the solvent used. Therefore, understanding its solubility profile requires careful assessment of solvent interactions.

In summary, the solubility of 2-phenyl-2-[2,4,6-triiodo-3-(2-oxomorpholin-4-yl)phenoxy]acetic acid is contingent on:

  1. The solvent's polarity
  2. The capacity for hydrogen bonding
  3. The influence of halogen substitutions

Ultimately, experimental data would be necessary to elucidate the precise solubility characteristics of this intriguing compound.

Interesting facts

Interesting Facts About 2-Phenyl-2-[2,4,6-triiodo-3-(2-oxomorpholin-4-yl)phenoxy]acetic Acid

The compound known as 2-phenyl-2-[2,4,6-triiodo-3-(2-oxomorpholin-4-yl)phenoxy]acetic acid is a fascinating example in the realm of organic chemistry, particularly due to its unique molecular structure and potential applications.

Structural Insights

  • Aromatic Character: This compound features a phenyl group attached to a phenoxy moiety, which results in significant aromatic stability.
  • Halogenation: The presence of multiple iodine substituents (triiodo) can greatly influence the compound's reactivity and by extension, its biological activity.
  • Morpholine Derivative: The inclusion of the morpholine ring suggests the potential for pharmacological applications, as many drugs utilize morpholinic structures to enhance solubility and binding properties.

Biological Significance

Research indicates that compounds with such halogen substitutions often show enhanced biological activities. For instance, they can exhibit:

  • Antimicrobial Activity: Halogenated organic compounds are frequently analyzed for their effects against various bacterial strains.
  • Anticancer Properties: Compounds with complex structures like this one are sometimes investigated for their ability to inhibit cancer cell proliferation.
  • Analgesic Effects: Thanks to their structural groups, these compounds may interact with pain receptors, providing potential for pain relief studies.

Synthesis Challenges

The synthesis of such a complex molecule typically involves intricate synthetic routes that can include:

  • Multi-step reactions that may require careful optimization.
  • The need for regioselective halogenation - a challenging aspect of organic synthesis.
  • Handling of toxic reagents typically associated with halogenation processes.

As one scientist quipped, "The beauty of organic chemistry lies in its complexity, where every bond tells a story." This compound is a prime illustration of that sentiment, embodying the intricate dance between structure, reactivity, and biological significance.