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Ioxaglic acid

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Identification
Molecular formula
C15H12I3NO4
CAS number
59017-51-5
IUPAC name
2-phenyl-2-[2,4,6-triiodo-3-[methyl(propanoyl)amino]phenoxy]acetic acid
State
State

At room temperature, ioxaglic acid exists in a solid state. It is stable and maintains its powdered form under typical storage conditions. It should be kept in a cool, dry place to prevent any degradation.

Melting point (Celsius)
225.00
Melting point (Kelvin)
498.15
Boiling point (Celsius)
196.00
Boiling point (Kelvin)
469.15
General information
Molecular weight
821.97g/mol
Molar mass
821.9700g/mol
Density
3.2390g/cm3
Appearence

Ioxaglic acid typically appears as a white crystalline powder. It is highly soluble in water, resulting in a clear solution when dissolved. The compound is odorless and is often used in medical imaging because of its iodine content, which enhances X-ray contrast.

Comment on solubility

Solubility of 2-phenyl-2-[2,4,6-triiodo-3-[methyl(propanoyl)amino]phenoxy]acetic acid

The solubility of 2-phenyl-2-[2,4,6-triiodo-3-[methyl(propanoyl)amino]phenoxy]acetic acid is influenced by several factors, including its molecular structure and the presence of functional groups. This compound contains both hydrophilic and hydrophobic segments, which contribute to its unique solubility profile:

  • Hydrophilic Characteristics: The presence of the acetic acid functional group likely enhances its ability to interact with polar solvents, increasing solubility in water.
  • Hydrophobic Characteristics: The aromatic phenyl groups and the iodine substituents introduce bulky and nonpolar elements, which can hinder solubility in aqueous environments.
  • Overall Solubility: The contestant balance between the hydrophilic and hydrophobic features suggests that the compound may exhibit limited solubility in water while potentially being more soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).

To summarize, while 2-phenyl-2-[2,4,6-triiodo-3-[methyl(propanoyl)amino]phenoxy]acetic acid may not be highly soluble in water, it could demonstrate enhanced solubility in organic or less polar solvents. Conducting systematic solubility tests across a range of solvents would provide more concrete insight into its behavior in various chemical environments. As always, understanding solubility properties is crucial in predicting the behavior of compounds in biological systems and industrial applications.

Interesting facts

Interesting Facts about 2-Phenyl-2-[2,4,6-triiodo-3-[methyl(propanoyl)amino]phenoxy]acetic Acid

This compound, often abbreviated for convenience in various scientific discussions, represents a fascinating intersection of organic chemistry and medicinal applications. Here are some intriguing points about this compound:

  • Structure Complexity: With the presence of multiple functional groups, such as the phenoxy and amidic structures, this compound showcases incredible structural diversity which influences its reactivity and potential applications in pharmaceuticals.
  • Triiodo Substitution: The incorporation of three iodine atoms is significant and can enhance the molecular stability while affecting the compound's biological activity, making it a subject of interest in medicinal chemistry.
  • Biological Activity: Compounds with similar structures have been studied for their potential in treating various conditions, including their roles as anti-inflammatory agents. The unique properties of the triiodo substitutions can lead to enhanced interactions with biological targets.
  • Application Potential: Similar compounds are being researched for their capabilities in imaging and therapy in medical fields, particularly in nuclear medicine.
  • Environmental Interactions: The presence of iodine may also influence the compound's behavior in environmental chemistry, hinting at the need for deeper studies on its stability and degradation in ecological systems.
  • Advanced Synthesis: The synthesis of such complex molecules often requires advanced techniques in organic synthesis, making the study of this compound a great learning opportunity for chemistry students.

As noted in discussions among scientific circles, "the understanding of complex organic compounds like this can pave the way for revolutionary advances in drug discovery and development." Consequently, 2-phenyl-2-[2,4,6-triiodo-3-[methyl(propanoyl)amino]phenoxy]acetic acid stands out not only for its intricate chemical structure but also for its promising prospects in both research and practical applications.

Synonyms
BRN 2913394
23189-36-8
2-(3-(N-Methylpropionamido)-2,4,6-triiodophenoxy)-2-phenylacetic acid
Acido 2-(3-N-metilpropionilamino-2,4,6-triiodofenossi)fenilacetico [Italian]
Benzeneacetic acid, alpha-(2,4,6-triiodo-3-(methyl(1-oxopropyl)amino)phenoxy)-
ACETIC ACID, 2-(3-(N-METHYLPROPIONAMIDO)-2,4,6-TRIIODOPHENOXY)-2-PHENYL-
Acido 2-(3-N-metilpropionilamino-2,4,6-triiodofenossi)fenilacetico
RefChem:316447
Benzeneacetic acid, alpha-(2,4,6-triiodo-3-(methyl(1-oxopropyl)amino)phenoxy)-(9CI)
DTXSID70945858
Phenyl{2,4,6-triiodo-3-[methyl(propanoyl)amino]phenoxy}acetic acid