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Ioxaglic acid

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Identification
Molecular formula
C11H9I3NO4
CAS number
59017-60-2
IUPAC name
2-phenyl-2-[2,4,6-triiodo-3-(propanoylamino)phenoxy]acetic acid
State
State

At room temperature, ioxaglic acid is commonly found in solid state in the form of a crystalline powder but may also be available in solution for specific applications.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
820.96g/mol
Molar mass
820.9600g/mol
Density
3.1200g/cm3
Appearence

Ioxaglic acid is a white or off-white crystalline solid that may appear as a powder. It is typically supplied in a sterile form for medical uses, often in aqueous solution.

Comment on solubility

Solubility of 2-phenyl-2-[2,4,6-triiodo-3-(propanoylamino)phenoxy]acetic acid

The solubility of 2-phenyl-2-[2,4,6-triiodo-3-(propanoylamino)phenoxy]acetic acid can be quite complex due to its chemical structure. Understanding solubility in this context requires considering several key factors:

  • Polarity: The presence of both hydrophobic (aromatic) and hydrophilic (carboxylic acid) groups suggests varying solubility in different solvents.
  • Hydrogen Bonding: The formation of intramolecular or intermolecular hydrogen bonds can significantly affect solubility.
  • Effect of Iodine Atoms: The three iodine atoms attached to the phenyl ring contribute to increased molecular weight and steric hindrance, which may lower solubility in water.
  • Solvent Considerations: This compound is likely to have limited solubility in polar solvents like water, but may dissolve better in organic solvents such as ethanol or acetone.

In summary, while the specific solubility values for 2-phenyl-2-[2,4,6-triiodo-3-(propanoylamino)phenoxy]acetic acid might be challenging to ascertain without empirical data, it's essential to appreciate the influence of structural features on solvation behavior. As the adage goes, "Like dissolves like," which underscores the importance of matching polarity between the solvent and solute for optimal solubility outcomes.

Interesting facts

Interesting Facts about 2-phenyl-2-[2,4,6-triiodo-3-(propanoylamino)phenoxy]acetic acid

This fascinating compound is a member of the phenolic acid family, showcasing a rich structure that offers multiple avenues for research and application. One of its most notable features is the presence of iodine atoms—specifically, three iodine groups that contribute not only to its chemical properties but also to its potential biological activity. The incorporation of iodine often enhances the compound's radiopacity, making it useful in various imaging applications.

Here are some key points about this compound:

  • Structure Complexity: The intricate arrangement of the phenyl groups and the unique propanoylamino substituent creates a versatile scaffold that can be further modified for diverse chemical reactions.
  • Biological Potential: Due to its unique molecular configuration, this compound could exhibit interesting biological properties, making it a candidate for further studies in medicinal chemistry.
  • Applications in Radiology: The triiodo substituents can enhance contrast in imaging, which has implications in diagnostic imaging technologies.
  • Research Interest: Chemists are continually exploring compounds like this for their potential use in pharmaceuticals, specifically as anti-cancer agents or in targeting specific biological pathways.

As noted by chemists in the field, "Compounds with complex structures often hold the keys to breakthrough discoveries in medicinal applications." This statement rings true for 2-phenyl-2-[2,4,6-triiodo-3-(propanoylamino)phenoxy]acetic acid, as ongoing research may unveil its full potential.

In summary, this compound is not just a chemical formula but a promising subject of study that could lead to innovations in various fields, from pharmaceuticals to analytical chemistry.

Synonyms
BRN 2911778
2-Phenyl-2-(3-propionamido-2,4,6-triiodophenoxy)acetic acid
23189-37-9
ACETIC ACID, 2-PHENYL-2-(3-PROPIONAMIDO-2,4,6-TRIODOPHENOXY)-
Acido 2-(3-propionilamino-2,4,6-triiodofenossi)fenilacetico [Italian]
Benzeneacetic acid, alpha-(2,4,6-triiodo-3-((1-oxopropyl)amino)phenoxy)-
Acido 2-(3-propionilamino-2,4,6-triiodofenossi)fenilacetico
RefChem:316526
Benzeneacetic acid, alpha-(2,4,6-triiodo-3-((1-oxopropyl)amino)phenoxy)-(9CI)
DTXSID30945859
{3-[(1-Hydroxypropylidene)amino]-2,4,6-triiodophenoxy}(phenyl)acetic acid