Interesting facts
Understanding 2-Phenyl-2-(p-tolyl)acetic Acid
2-Phenyl-2-(p-tolyl)acetic acid is a fascinating compound that falls under the category of aromatic carboxylic acids. Here are some interesting aspects of this compound:
- Aromatic Structure: The presence of two phenyl groups in its structure contributes to its unique properties, including enhanced stability and characteristic reactivity.
- Reactivity: This compound displays typical reactivity of carboxylic acids, making it versatile in organic synthesis and allowing it to participate in various chemical reactions, such as esterification and amidation.
- Pharmaceutical Implications: The parent compound's structural features have inspired derivatives that play roles in pharmaceuticals, particularly in the development of anti-inflammatory and analgesic medications.
- Applications in Synthesis: It serves as a crucial building block in organic chemistry, enabling the formation of more complex molecules through reactions like the Grignard reaction or Friedel-Crafts reactions.
- Biological Interest: Given its structural relationship to other bioactive compounds, 2-phenyl-2-(p-tolyl)acetic acid can be a target for studying various biological activities and mechanisms.
In conclusion, 2-phenyl-2-(p-tolyl)acetic acid exemplifies the intersection of organic chemistry and pharmaceuticals, showcasing how fundamental compounds can lead to innovative applications in health and industry. As researchers continue to explore its derivatives, the potential for discovering new therapeutic agents remains promising.
Synonyms
1882-56-0
2-(4-Methylphenyl)-2-phenylacetic acid
Phenyl(p-tolyl)acetic acid
(4-methylphenyl)(phenyl)acetic acid
ACETIC ACID, PHENYL-p-TOLYL-
2-Phenyl-2-(p-tolyl)aceticacid
Benzeneacetic acid, 4-methyl-alpha-phenyl-
2-phenyl-2-(p-tolyl)acetic acid
MFCD00983826
Benzeneacetic acid, 4-methyl-.alpha.-phenyl-
NSC 401984
4-Methyl-alpha-phenylbenzeneacetic acid
BRN 2105437
NSC401984
Phenyl-p-tolylessigsaure
4-09-00-02541 (Beilstein Handbook Reference)
F2184-0205
SCHEMBL1551142
JYDAJZSDPZCZSG-UHFFFAOYSA-N
DTXSID001295111
AR3875
AKOS015957356
NSC-401984
4-Methyl-I+/--phenylbenzeneacetic acid
2-(4-Methyl-phenyl)-2-phenyl-acetic acid
CS-0172122
EN300-234741
1W-0676
Solubility of 2-phenyl-2-(p-tolyl)acetic acid
2-phenyl-2-(p-tolyl)acetic acid is an intriguing compound when it comes to its solubility characteristics. This compound, being an aromatic compound with two phenyl groups, exhibits some unique behavior in various solvents:
In conclusion, the solubility profile of 2-phenyl-2-(p-tolyl)acetic acid reflects its molecular structure, where the presence of bulky phenyl groups impedes solubility in polar solvents like water, while enhancing compatibility with non-polar and moderately polar solvents. As the saying goes, "like dissolves like," and this compound is a prime example of that principle in action.