Skip to main content

2-phenyl-2H-1,3,4-oxadiazol-5-one

ADVERTISEMENT
Identification
Molecular formula
C8H6N2O2
CAS number
20116-89-2
IUPAC name
2-phenyl-2H-1,3,4-oxadiazol-5-one
State
State

At room temperature, 2-phenyl-2H-1,3,4-oxadiazol-5-one exists as a solid. It is stable under normal conditions and should be stored away from strong oxidizing agents to prevent any potential hazardous reactions.

Melting point (Celsius)
159.00
Melting point (Kelvin)
432.15
Boiling point (Celsius)
244.00
Boiling point (Kelvin)
517.15
General information
Molecular weight
160.14g/mol
Molar mass
160.1440g/mol
Density
1.2960g/cm3
Appearence

2-Phenyl-2H-1,3,4-oxadiazol-5-one is typically found as a crystalline solid. It can vary in color from white to slightly off-white, depending on the purity and specific form. The compound has a non-distinct odor.

Comment on solubility

Solubility of 2-phenyl-2H-1,3,4-oxadiazol-5-one

2-phenyl-2H-1,3,4-oxadiazol-5-one, a compound of interest in various fields, exhibits intriguing solubility characteristics. Understanding the solubility of such compounds is crucial as it affects their bioavailability, reactivity, and potential applications.

Key Points on Solubility:

  • Polarity: The presence of the oxadiazole group likely imparts some polarity to the molecule, which can influence its solubility in polar solvents.
  • Solvent Compatibility: It is generally expected to be more soluble in organic solvents, such as dichloromethane and ethanol, than in water.
  • Temperature Effects: Solubility may increase with temperature, as is common with many organic compounds.
  • Hydrogen Bonding: The potential for hydrogen bonding with solvents may also play a significant role in enhancing its solubility.

In conclusion, the solubility of 2-phenyl-2H-1,3,4-oxadiazol-5-one suggests that it may find applications in various organic reactions where solvent choice is critical. As with any chemical, it’s vital to refer to specific experimental data to ascertain exact solubility parameters for this intriguing compound.

Interesting facts

Interesting Facts about 2-Phenyl-2H-1,3,4-oxadiazol-5-one

2-Phenyl-2H-1,3,4-oxadiazol-5-one is a fascinating compound widely studied for its diverse applications in various fields of chemistry. Here are some highlights that make this compound particularly interesting:

  • Pharmaceutical Potential: This compound is known for its biological activity, making it a candidate for drug development, especially in anti-inflammatory and antimicrobial therapies.
  • Fluorescent Properties: The oxadiazole moiety is known to exhibit excellent fluorescence, enabling its use in the creation of optical sensors, fluorescent labels, and other photonic devices.
  • Versatile Chemistry: 2-Phenyl-2H-1,3,4-oxadiazol-5-one serves as an important building block in organic synthesis, allowing chemists to create complex molecules through various reactions.
  • Incorporation in Polymers: Researchers have investigated its incorporation into polymeric materials, which has promising implications for enhancing material properties, such as thermal stability and mechanical strength.
  • Mechanistic Studies: The study of this compound can provide insights into the mechanisms of heterocyclic compound behavior, crucial for developing new materials and understanding chemical reactivity.

Moreover, as a member of the oxadiazole family, it shares structural features that are pivotal in designing molecules with specific electronic properties, which is essential for advancements in materials science. Its unique structure not only contributes to its activity and applications but also sparks curiosity about its potential in innovative research.

As one scientist put it, "Understanding compounds like 2-phenyl-2H-1,3,4-oxadiazol-5-one bridges the gap between fundamental chemistry and applied science." This illustrates the compound's significance in both theoretical and practical realms.

Synonyms
2-phenyl-2H-1,3,4-oxadiazol-5-one
delta(sup 2)-1,3,4-OXADIAZOLIN-5-ONE, 2-PHENYL-
NSC 525342
2-Phenyl-delta(sup 2)-1,3,4-oxadiazolin-5-one
SCHEMBL10833990
5-PHENYL-5H-1,3,4-OXADIAZOL-2-ONE
F83058