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2-phenylimidazoline

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Identification
Molecular formula
C9H10N2
CAS number
936-50-5
IUPAC name
2-phenyl-4,5-dihydro-1H-imidazole
State
State

The compound is in a solid state at room temperature.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
146.19g/mol
Molar mass
146.1910g/mol
Density
1.0900g/cm3
Appearence

2-Phenylimidazoline typically appears as a white to off-white crystalline solid. The compound can be characterized by its crystalline structure and solid form at room temperature.

Comment on solubility

Solubility of 2-phenyl-4,5-dihydro-1H-imidazole

2-phenyl-4,5-dihydro-1H-imidazole, with its intriguing molecular structure, presents interesting challenges and characteristics related to solubility.

Generally, the factors affecting the solubility of this compound include:

  • Polarity: The presence of the imidazole ring may impart some polarity, influencing its interaction with polar solvents.
  • Hydrophobic Phenyl Group: The phenyl substituent contributes to hydrophobic interactions, making the compound less soluble in water.
  • Specific Interactions: Hydrogen bonding capabilities of imidazole may enhance solubility in particular organic solvents.

Typically, 2-phenyl-4,5-dihydro-1H-imidazole exhibits moderate solubility in organic solvents such as ethanol and DMSO, while its solubility in water is limited. This limited solubility can be quantified by stating that it may dissolve to a small extent, reflecting the balance between the polar and non-polar attributes of the molecule.

In summary, understanding the solubility characteristics of 2-phenyl-4,5-dihydro-1H-imidazole is crucial for its applications, particularly in pharmaceutical formulations and chemical synthesis.

Interesting facts

Interesting Facts About 2-Phenyl-4,5-dihydro-1H-imidazole

2-Phenyl-4,5-dihydro-1H-imidazole is a fascinating compound that draws attention in the field of organic chemistry due to its unique structural characteristics and diverse applications. Here are some engaging insights:

  • Structural Significance: The imidazole ring is a five-membered aromatic compound that plays an essential role in biology, notably as part of the structure of histidine, a critical amino acid.
  • Pharmaceutical Potential: Compounds containing imidazole derivatives, including 2-phenyl-4,5-dihydro-1H-imidazole, have been investigated for their biological activities, often exhibiting anti-inflammatory, antifungal, and antibacterial properties.
  • Versatility: The phenyl group attached to the imidazole enhances the compound's ability to act as a ligand in coordination chemistry, making it useful in the formation of complex compounds with transition metals.
  • Reaction Behavior: This compound can participate in various chemical reactions such as electrophilic substitutions and cycloadditions, contributing to its versatility in chemical synthesis.
  • Research Interest: Its structural analogs are being studied for their potential in developing new therapeutic agents, especially in the fight against resistant strains of bacteria and fungi.

In summary, 2-phenyl-4,5-dihydro-1H-imidazole is not just a chemical compound; it's a valuable entity in scientific research with promising implications in medicine and materials science. As chemists continue to explore its properties and reactions, we may see new breakthroughs that harness the unique characteristics of this intriguing compound.

Synonyms
2-Phenyl-2-imidazoline
936-49-2
2-Phenylimidazoline
1H-Imidazole, 4,5-dihydro-2-phenyl-
2-IMIDAZOLINE, 2-PHENYL-
NSC 54747
EINECS 213-313-4
BRN 0119250
DTXSID5061322
EC 213-313-4
5-23-06-00425 (Beilstein Handbook Reference)
DTXCID7048875
213-313-4
2-Phenyl-4,5-dihydro-1H-imidazole
4,5-Dihydro-2-phenyl-1H-imidazole
CHEMBL274548
NSC-54747
2-Imidazoline, 2-phenyl- (6CI,7CI,8CI); 2-Phenyl-2-imidazoline
MFCD00005180
2-phenyl imidazoline
2-Phenyl-1H-Imidazoline
SCHEMBL105024
2-Phenyl-4,5-dihydroimidazole
4,5-dihydro-2-phenylimidazole
E78R99DCH8
1H-Imidazole,5-dihydro-2-phenyl-
AAA93649
NSC54747
STR05026
BDBM50240363
STK367860
AKOS001429412
2-Phenyl-4,5-dihydro-1H-imidazole #
AC-11337
2-Phenyl-2-imidazoline, >=96% (HPLC)
CS-0008348
NS00008391
P0685
EN300-29510
D78018
Q63392122
F1995-0381
Z283858536