2-phenyl-N'-propyl-acetamidine | Solubility of Things

Identification

Molecular formula

C₁₁H₁₆N₂

CAS number

861394-71-4

IUPAC name

2-phenyl-N'-propyl-acetamidine

State

At room temperature, 2-phenyl-N'-propyl-acetamidine is in a liquid state. It is characteristically used in its liquid form for various chemical synthesis processes.

Melting point (Celsius)

-5.00

Melting point (Kelvin)

268.15

Boiling point (Celsius)

289.00

Boiling point (Kelvin)

562.15

General information

Molecular weight

160.26g/mol

Molar mass

160.2560g/mol

Density

0.9634g/cm³

Appearence

2-phenyl-N'-propyl-acetamidine typically appears as a colorless or pale yellow liquid. It is commonly used in organic synthesis as a reagent, and its liquid state at room temperature makes it convenient for various applications.

Comment on solubility

Solubility of 2-phenyl-N'-propyl-acetamidine

2-phenyl-N'-propyl-acetamidine exhibits varying solubility characteristics that can significantly influence its applications in chemical research and synthesis. Understanding the solubility of this compound in different solvents is crucial for optimizing its use. Here are some key points regarding its solubility:

Solvent Dependency: The solubility of 2-phenyl-N'-propyl-acetamidine can vary widely depending on the solvent used. For instance, it is typically more soluble in polar solvents such as ethanol and methanol compared to less polar solvents.
Temperature Influence: Increasing temperature often enhances solubility. Therefore, higher temperatures can facilitate the dissolution of 2-phenyl-N'-propyl-acetamidine in appropriate solvents.
pH Sensitivity: The compound may show altered solubility at different pH levels, particularly when ionizable groups are present. This is an important consideration in biological or synthetic environments.
Practical Applications: Due to its unique solubility profile, it can be utilized in pharmaceutical formulations where specific solubility is desired for effective drug delivery and absorption.

In summary, the solubility of 2-phenyl-N'-propyl-acetamidine is influenced by multiple factors including solvent choice, temperature, and pH. Understanding these aspects is key for harnessing the compound's potential in various chemical applications.

Interesting facts

Interesting Facts about 2-phenyl-N'-propyl-acetamidine

2-phenyl-N'-propyl-acetamidine is a fascinating compound that falls within the category of amidines, which are derivatives of amines. Here are some intriguing aspects of this compound:

Biological Activity: This compound has shown potential in biological activities, making it of interest in medicinal chemistry. Its derivatives can act as important intermediates in the synthesis of pharmacologically active agents.
Structure & Reactivity: The presence of a phenyl group and an acetamidine moiety contributes to its unique reactivity profile, allowing it to participate in various chemical reactions that can be exploited for synthetic purposes.
Applications: Beyond synthetic chemistry, amidines like 2-phenyl-N'-propyl-acetamidine can be useful in various applications, including:
- As ligands in coordination chemistry
- In the production of agrochemicals
- Potentially as new therapeutic agents due to their bioactivity
Research Potential: Due to the unique properties of amidines, ongoing research is being conducted to explore their potential uses in various fields, including:
- Drug design
- Material science
- Catalysis
Historical Context: Amidines have been known in organic chemistry since the 19th century and continue to be a vital area of exploration for chemists today, showcasing the evolution of compound understanding over time.

In summary, 2-phenyl-N'-propyl-acetamidine represents a small but significant piece of the broad tapestry of organic chemistry. Its structural uniqueness and the implications for biological activity make it an exciting target for current and future research endeavors.

Synonyms

2-Phenyl-N-propyl-acetamidine

benzene, (N-propyl)amidinomethyl-

AKOS011326831