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N-Trimethylsilyl-2-phenylethylamine

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Identification
Molecular formula
C11H19NSi
CAS number
939-34-6
IUPAC name
2-phenyl-N-trimethylsilyl-ethanamine
State
State

At room temperature, N-Trimethylsilyl-2-phenylethylamine is in the liquid state. Its clear appearance and low freezing point favor its liquid form under standard conditions.

Melting point (Celsius)
-15.00
Melting point (Kelvin)
258.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
177.34g/mol
Molar mass
177.3380g/mol
Density
0.8890g/cm3
Appearence

N-Trimethylsilyl-2-phenylethylamine is a clear and colorless to pale yellow liquid. It is typically transparent and has a slight characteristic odor.

Comment on solubility

Solubility of 2-phenyl-N-trimethylsilyl-ethanamine

2-phenyl-N-trimethylsilyl-ethanamine (C11H19NSi) exhibits unique solubility characteristics that are worth noting:

  • Polar and Nonpolar Interactions: Given its structure, the presence of the trimethylsilyl group confers some degree of hydrophobicity, which can influence its solubility in organic solvents compared to polar solvents.
  • Solvents: It is generally more soluble in nonpolar organic solvents such as hexane or diethyl ether, while demonstrating limited solubility in water due to the nonpolar characteristics imparted by the phenyl and silyl groups.
  • Concentration Dependency: The solubility may be concentration-dependent; at higher concentrations, precipitation may occur, indicating a limit to its solubility in a given solvent.
  • Temperature Influence: As with many compounds, increasing temperature typically enhances solubility in organic solvents; however, this can also lead to the decomposition of sensitive compounds.

To summarize, the solubility of 2-phenyl-N-trimethylsilyl-ethanamine is primarily influenced by the balance of its polar and nonpolar characteristics, making it more suited for nonpolar environments while exhibiting limited solubility in aqueous conditions.

Interesting facts

Interesting Facts about 2-phenyl-N-trimethylsilyl-ethanamine

2-phenyl-N-trimethylsilyl-ethanamine is a fascinating compound that finds its utility in various areas of chemical research and applications. Here are some intriguing aspects of this compound:

  • Silicon Integration: The presence of the trimethylsilyl group makes this compound significant in organosilicon chemistry, contributing to its unique reactivity and stability. This silicon modification can enhance properties such as solubility and volatility.
  • Pharmaceutical Applications: Compounds with amine functionalities are often pivotal in drug discovery. The phenyl group can increase lipophilicity, potentially making derivatives of this compound of interest for medicinal chemistry.
  • Versatile Reactions: The amine group allows for a variety of chemical transformations. 2-phenyl-N-trimethylsilyl-ethanamine can participate in nucleophilic substitutions, making it a versatile intermediate in synthetic chemistry.
  • Chiral Synthesis Potential: This compound can be used in asymmetric synthesis, where the chirality of the reactants is crucial for producing specific enantiomers. The chiral environment around the nitrogen can steer the reactions towards desired products.
  • Influence on Reaction Conditions: The presence of a trimethylsilyl group can affect reaction conditions, such as temperature and solvent choice, leading to improved yields and selectivity in chemical reactions.

In summary, 2-phenyl-N-trimethylsilyl-ethanamine is more than just a chemical formula; it embodies a bridge between silicon chemistry and organic synthesis, offering numerous pathways for exploration in both academic and industrial chemistry.

Synonyms
10433-33-7
BRN 2716449
SILANAMINE, N-(2-PHENYLETHYL)-1,1,1-TRIMETHYL-
Phenethylamine, TMS derivative
Silylamine, 1,1,1-trimethyl-N-phenethyl-
Silanamine, 1,1,1-trimethyl-N-(2-phenylethyl)-
DTXSID20146393
4-12-00-02488 (Beilstein Handbook Reference)
DTXCID8068884
ijdngnisllhucn-uhfffaoysa-n
N-(2-Phenylethyl)-1,1,1-trimethylsilanamine
N-(Trimethylsilyl)-N-(2-phenylethyl)amine
2-phenyl-N-trimethylsilylethanamine
MFCD01684186
trimethylsilylphenethylamine
SCHEMBL6560133
N-(2-Phenylethyl)-N-(trimethylsilyl)amine #