Skip to main content

Acetanilide

ADVERTISEMENT
Identification
Molecular formula
C8H9NO
CAS number
103-84-4
IUPAC name
2-phenylacetamide
State
State

Acetanilide is a solid at room temperature. It does not liquefy into a gas unless it reaches its boiling point of 304 °C which is 577.15 K.

Melting point (Celsius)
114.30
Melting point (Kelvin)
387.45
Boiling point (Celsius)
304.00
Boiling point (Kelvin)
577.15
General information
Molecular weight
135.17g/mol
Molar mass
135.1650g/mol
Density
1.2190g/cm3
Appearence

Acetanilide appears as a white solid, often in the form of flakes or a crystalline powder. It is known for its slight and pleasant odor. The compound tends to yellow slightly upon exposure to light or upon standing.

Comment on solubility

Solubility of 2-Phenylacetamide

2-Phenylacetamide, with the chemical formula C9H11NO, exhibits interesting solubility characteristics that are worth noting:

  • Solvent Interaction: This compound is known to be soluble in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), and chloroform, while displaying limited solubility in water.
  • Water Solubility: The low solubility in water can be attributed to its hydrophobic phenyl group, which tends to minimize interaction with polar water molecules.
  • Temperature Dependency: The solubility of 2-phenylacetamide may increase at elevated temperatures, a common trait among many organic compounds.

Overall, understanding the solubility profile of 2-phenylacetamide is crucial for its applications in various chemical processes. The ability to dissolve in organic solvents while remaining insoluble in water emphasizes its behavior as a non-polar compound, influencing its reactivity and suitability in reactions involving polar media.

Interesting facts

Interesting Facts about 2-Phenylacetamide

2-Phenylacetamide is an intriguing compound that has caught the attention of researchers and chemists alike. Here are some fascinating aspects of this chemical:

  • Versatile Derivative: 2-Phenylacetamide is often regarded as a versatile compound in organic synthesis. It serves as a precursor for the synthesis of various pharmaceuticals and agrochemicals.
  • Biological Activity: Studies have shown that this compound exhibits notable biological properties. For instance, it has demonstrated analgesic and anti-inflammatory activities, making it a subject of interest for medicinal chemistry.
  • Structural Significance: The presence of the phenyl group in 2-phenylacetamide contributes to its stability and reactivity. The unique arrangement affects how the compound interacts with biological systems.
  • Amide Group: The amide functional group present in this compound plays a crucial role in its ability to form hydrogen bonds, which enhances solubility in certain organic solvents.

In the words of renowned chemists, "The structure of a compound defines its destiny." This profound statement is particularly relevant for 2-phenylacetamide, as its structural attributes allow it to participate in various chemical reactions.

As researchers continue to explore its properties and applications, 2-phenylacetamide is likely to remain an important compound in the fields of chemistry and pharmacology.


Synonyms
2-PHENYLACETAMIDE
103-81-1
Phenylacetamide
Benzeneacetamide
alpha-Toluamide
Phenylacetic acid amide
alpha-Phenylacetamide
Acetamide, 2-phenyl-
Phenyl-beta-acetylamine
alpha-Toluimidic acid
.alpha.-Toluamide
2-phenyl-Acetamide
phenacetamide
.alpha.-Phenylacetamide
Phenyl-.beta.-acetylamine
.alpha.-Toluimidic acid
CHEBI:16562
2-Acetanilide
NSC 1877
EINECS 203-147-0
5R219M9TJF
GNF-PF-1199
AI3-19421
BENZENEDIACETAMIDE
NSC-1877
MFCD00059193
CHEMBL347645
DTXSID1059282
.ALPHA.-PHENYLACETAMIDE [MI]
UNII-5R219M9TJF
alphaToluamide
2phenylacetamide
phenyl acetamide
benzene-acetamide
Acetamide, 2phenyl
alphaToluimidic acid
Phenylbetaacetylamine
phenylacetimidic acid
Acetamide, 2-phenyl
(+)-benzeneacetamide
(-)-benzeneacetamide
beta-Phenyl-acetylamine
(+/-)-benzeneacetamide
(alpha-)2-Phenylacetamide
2-Phenylacetamide(alpha-)
SCHEMBL25676
Phenylacetamide;alpha-Toluamide
DTXCID1032771
NSC1877
BCP10408
BDBM50226209
s4440
AKOS001215073
CS-W018983
HY-W018197
AC-24581
FP139317
PD155928
SY017094
DB-021492
NS00023262
P0120
EN300-15619
C02505
Q27101974
Z33546508
F1084-0941
46AFC744-1FF7-4816-B1C1-7C9995F369E8
203-147-0