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Acridine Orange

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Identification
Molecular formula
C13H10N2
CAS number
3248-14-6
IUPAC name
2-phenylacridin-9-amine
State
State

This compound is typically in a solid state at room temperature.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
433.00
Boiling point (Kelvin)
706.15
General information
Molecular weight
194.23g/mol
Molar mass
244.3000g/mol
Density
1.2290g/cm3
Appearence

Acridine Orange appears as an orange to yellowish powder that fluoresces under ultraviolet light. It is often used as a fluorescent dye in various biological staining methods, including nucleic acids.

Comment on solubility

Solubility of 2-phenylacridin-9-amine

2-phenylacridin-9-amine, a fascinating compound with a complex structure, exhibits unique solubility characteristics that are vital for its applications. Understanding its solubility is crucial, as it impacts its behavior in various solvents and environments.

Solubility Characteristics

The solubility of 2-phenylacridin-9-amine can be influenced by several factors:

  • Polarity of the Solvent: This compound tends to show variable solubility based on the solvent used. Generally, it is more soluble in polar solvents such as dimethyl sulfoxide (DMSO) or dimethylformamide (DMF) due to its polar amine group.
  • Aromatic Nature: The presence of aromatic rings often leads to stronger hydrophobic interactions, potentially limiting solubility in non-polar solvents.
  • Temperature: Higher temperatures can increase solubility, facilitating better molecular interactions in solvents.

As with many complex compounds, it's essential to consider specific interactions and conditions under which solubility is tested. In summary, while 2-phenylacridin-9-amine tends to be soluble in polar environments, its solubility in organic solvents can be more limited due to its structural features. Testing in various conditions can provide more insight into its behavior.

Interesting facts

Interesting Facts About 2-Phenylacridin-9-amine

2-Phenylacridin-9-amine, also known as a derivative of acridine, is a fascinating compound that has garnered interest in various fields of chemistry and material science. This compound showcases a rich chemistry due to its unique structure and properties, making it a subject of ongoing research. Here are some key points that highlight its significance:

  • Fluorescent Properties: 2-Phenylacridin-9-amine exhibits notable fluorescence, which is useful in applications such as fluorescence microscopy and as fluorescent markers in biological research.
  • Potential Anticancer Activity: Studies have indicated that acridine derivatives, including 2-phenylacridin-9-amine, possess significant anticancer properties. This positions them as potential candidates for the development of new anticancer drugs.
  • Versatile Applications: The compound is being explored for various applications, including:
    • Organic light-emitting diodes (OLEDs)
    • Photodetectors
    • As a dye in textile applications
  • Role in Coordination Chemistry: The amine group in 2-phenylacridin-9-amine enables it to participate in coordination with metal ions, making it useful for the development of coordination compounds.
  • Research Frontiers: Ongoing research is focused on modifying the compound to enhance its photophysical properties, thereby broadening its applicability in materials science.

In summary, the versatile characteristics of 2-phenylacridin-9-amine not only enhance its appeal in the realm of academia but also raise exciting possibilities for practical applications. As noted by researchers, "The exploration of acridine derivatives opens doors to new chemotherapeutic agents and advanced materials."

Synonyms
ACRIDINE, 9-AMINO-2-PHENYL-
9-Acridinamine, 2-phenyl-
BRN 0211234
5949-66-6
5-Amino-3-phenylacridine (European)
DTXSID40208189
5-22-11-00198 (Beilstein Handbook Reference)
DTXCID10130680
TCMDC-132030
CHEMBL549012
SCHEMBL11060743