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2-Phenylbutyric acid

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Identification
Molecular formula
C10H12O2
CAS number
2506-34-9
IUPAC name
2-phenylbutanoic acid
State
State

At room temperature, 2-Phenylbutyric acid is typically in a solid state, characterized by its crystalline structure.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.00
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.00
General information
Molecular weight
164.20g/mol
Molar mass
164.2040g/mol
Density
1.0300g/cm3
Appearence

2-Phenylbutyric acid appears as a white crystalline solid. It possesses a characteristic aromatic odor that is often associated with its phenyl group.

Comment on solubility

Solubility of 2-Phenylbutanoic Acid

2-Phenylbutanoic acid, with the chemical formula C10H12O2, exhibits some interesting characteristics concerning its solubility:

  • Solvent Compatibility: It shows moderate solubility in organic solvents such as ethanol and acetone, owing to its hydrophobic aromatic ring and the hydrophilic carboxylic acid group.
  • Water Solubility: Generally, 2-phenylbutanoic acid is poorly soluble in water. This limited solubility is primarily due to the non-polar nature of the phenyl group, which reduces its ability to interact effectively with polar water molecules.
  • Temperature Effect: As with many organic compounds, solubility can increase with higher temperatures, which facilitates the dissolution of the molecule in various solvents.

In summary, while 2-phenylbutanoic acid can dissolve in certain organic solvents, its solubility in water is quite limited, highlighting the significant role of molecular structure in determining solubility behaviors:

"The intriguing balance between hydrophilic and hydrophobic properties shapes the solubility landscape of compounds."
Interesting facts

Interesting Facts About 2-Phenylbutanoic Acid

2-Phenylbutanoic acid is a fascinating compound that has garnered attention in various fields of chemistry, particularly in organic synthesis and pharmaceutical research. Here are some intriguing points about this compound:

  • Structural Significance: This compound features a unique structure with a phenyl ring attached to a four-carbon butanoic acid chain. This positioning significantly influences its chemical properties and reactions.
  • Synthesis and Applications: 2-Phenylbutanoic acid can be synthesized through various methods, using intermediates and reagents that are common in organic synthesis. Its derivatives are often researched for their potential applications in the development of anti-inflammatory and analgesic medications.
  • Biological Relevance: The compound is notable for its interactions with biological systems. For instance, it exhibits properties related to the modulation of certain biochemical pathways, making it a point of interest in pharmacology.
  • Chirality: The compound can exist in different stereochemical forms. Understanding its chiral centers is critical for predicting its biological activity, highlighting the importance of stereochemistry in drug design.
  • Environmental Impact: Like many organic acids, 2-phenylbutanoic acid is studied for its biodegradability and environmental persistence. Such analyses ensure the use of such compounds does not pose a threat to ecosystems.

In summary, 2-phenylbutanoic acid stands out for its diverse applications and significant role in advancing our understanding of organic compounds. As noted by chemists, "Every compound tells a story," and this one is no exception!

Synonyms
2-Phenylbutyric acid
2-Phenylbutanoic acid
90-27-7
alpha-Ethylphenylacetic acid
Butyric acid, 2-phenyl-
Benzeneacetic acid, .alpha.-ethyl-
alpha-Phenylbutyric acid
alpha-Phenyl butyric acid
Benzeneacetic acid, alpha-ethyl-
NSC 1860
(+/-)-2-Phenylbutyric acid
alpha-Toluic acid, alpha-ethyl-
EINECS 201-982-5
MFCD00002667
alpha-Ethyl-alpha-toluic acid
BRN 0509876
CHEBI:86545
2-phenyl-butyric acid
AI3-11228
NSC1860
a-Ethylphenylacetic acid
S7S079H2C2
NSC-1860
.alpha.-Phenylbutyric acid
(RS)-2-Phenylbutanoic acid
(2RS)-2-Phenylbutanoic Acid
DTXSID90861682
2-09-00-00356 (Beilstein Handbook Reference)
.alpha.-Toluic acid, .alpha.-ethyl-
PRIMIDONE IMPURITY E [EP IMPURITY]
PRIMIDONE IMPURITY E (EP IMPURITY)
2-Phenylbutanoicacid
2-Phenylburyric acid
2-Ethyl-2-phenylacetic Acid
UNII-S7S079H2C2
a-Phenylbutyrate
(2RS)-2-Phenylbutanoic Acid; Primidone Imp. E (EP); Primidone Impurity E
2-Phenylbutyrate
2-phenylbutanoate
a-Ethyl-a-toluate
a-Ethylphenylacetate
alpha-Phenylbutyrate
phenyl butanoic acid
a-Ethylbenzeneacetate
a-Ethyl-a-toluic acid
alpha-Ethylphenylacetate
Spectrum_001673
alpha-Ethylbenzeneacetate
SpecPlus_000897
a-Ethylbenzeneacetic acid
(RS)-2-Phenylbutanoate
alpha-Ethyl-alpha-toluate
Spectrum2_000510
Spectrum3_001664
Spectrum4_000626
Spectrum5_001396
(+)2-phenylbutyric acid
bmse000617
A-PHENYLBUTYRIC ACID
Cambridge id 5132265
SCHEMBL1715
WLN: QVY2&R
.alpha.-Phenyl butyric acid
alpha-Ethylbenzeneacetic acid
2-Phenylbutyric acid, 98%
BSPBio_003447
KBioGR_001212
KBioSS_002153
DivK1c_006993
.alpha.-Ethylphenylacetic acid
SPBio_000439
.alpha.-Phenyl-n-butyric acid
CHEMBL1616045
KBio1_001937
KBio2_002153
KBio2_004721
KBio2_007289
KBio3_002667
DTXCID40810569
(.+/-.)-2-Phenylbutyric acid
2-Phenylbutanoic acid (Standard)
(.+/-.)-2-Phenylbutanoic acid
ALBB-023513
HY-W017194R
BBL012274
s6086
STL163589
AKOS000120324
AKOS016040111
(+/-)-2-PHENYLBUTANOIC ACID
BS-3887
CS-W017910
FP26945
HY-W017194
SB44765
AC-10409
PD065554
SY036812
DB-070362
DB-079726
NS00041253
P0164
EN300-20606
E78161
2-Ethyl-2-phenylacetic acid;Primidone impurity E
Q27159231
F2191-0104
Z104479150
(+/-)-2-Phenylbutyric acid, Vetec(TM) reagent grade, 98%
201-982-5
InChI=1/C10H12O2/c1-2-9(10(11)12)8-6-4-3-5-7-8/h3-7,9H,2H2,1H3,(H,11,12