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Phenethylamine

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Identification
Molecular formula
C8H11N
CAS number
64-04-0
IUPAC name
2-phenylethanamine
State
State

At room temperature, phenethylamine is a liquid. It can be easily volatile and is soluble in water and ether.

Melting point (Celsius)
-60.00
Melting point (Kelvin)
213.15
Boiling point (Celsius)
195.00
Boiling point (Kelvin)
468.15
General information
Molecular weight
121.18g/mol
Molar mass
121.1790g/mol
Density
0.9640g/cm3
Appearence

Phenethylamine is a colorless liquid which can sometimes appear as a yellowish liquid due to impurities. It has a fishy, ammoniacal odor.

Comment on solubility

Solubility of 2-phenylethanamine (C8H11N)

2-phenylethanamine, commonly known as phenylethylamine, exhibits intriguing solubility characteristics. When evaluating its solubility, it's essential to consider its molecular structure and the presence of the amine group, which influences its interactions with solvents.

Factors Affecting Solubility

  • Polarity: Being an amine, 2-phenylethanamine is polar, which allows it to dissolve in polar solvents such as water to a certain extent.
  • Nonpolarity: The hydrophobic aromatic ring contributes to its solubility in nonpolar organic solvents like benzene and toluene.
  • Hydrogen Bonding: 2-phenylethanamine can form hydrogen bonds with water, enhancing its solubility compared to non-amine compounds.

In summary, 2-phenylethanamine is moderately soluble in water and highly soluble in nonpolar solvents. Its unique combination of hydrophilic and hydrophobic characteristics makes it a compound of interest in various applications.

Interesting facts

Interesting Facts about 2-phenylethanamine

2-phenylethanamine, commonly known as phenethylamine, is a fascinating amine compound that plays a significant role in both chemistry and biology. Here are some captivating insights about this compound:

  • Biological Significance: 2-phenylethanamine occurs naturally in the human body and is thought to act as a neurotransmitter, influencing mood and behavior. It has been linked to feelings of euphoria and pleasure, often referred to as the "love chemical."
  • Precursor to Various Compounds: This compound serves as a crucial precursor for several important substances, including neurotransmitters like dopamine and norepinephrine, which are vital for cognitive function and mood regulation.
  • Use in the Food Industry: 2-phenylethanamine is known for its *floral and sweet aroma*, and it is sometimes used in fragrances and flavorings, enhancing the sensory appeal of various food products.
  • Potential Therapeutic Applications: Research is ongoing into the therapeutic potentials of 2-phenylethanamine in treating conditions like depression and ADHD. As a stimulating compound, it is being studied for its effects on enhancing cognitive performance.
  • Structural Characteristics: The structure of 2-phenylethanamine features a phenyl group attached to an ethylamine moiety, making it an example of a *primary amine.* Its simple structure allows for various functionalization, leading to a wide array of derivatives.

In conclusion, 2-phenylethanamine is more than just a chemical compound; it bridges the gap between chemistry, neuroscience, and industry. As scientists continue to explore its properties and potential applications, the relevance of this compound in both academic and practical settings is bound to grow.

Synonyms
Phenethylamine
2-phenylethylamine
2-Phenylethanamine
64-04-0
Benzeneethanamine
2-Phenethylamine
phenylethylamine
beta-phenylethylamine
beta-Phenethylamine
1-Amino-2-phenylethane
beta-Aminoethylbenzene
(2-Aminoethyl)benzene
1-Phenyl-2-aminoethane
2-Amino-1-phenylethane
Ethanamine, 2-phenyl-
Ethylamine, 2-phenyl-
2-Phenylethan-1-Amine
1-Phenyl-2-amino-athan
2-Fenylethylamin
2-Amino-fenylethan
PHENETHYLAMINE, BETA
b-phenylethylamine
2-Fenylethylamin [Czech]
beta-Phenylaethylamin
2-Amino-fenylethan [Czech]
.beta.-Phenylethylamine
beta-Phenylaethylamin [German]
FEMA No. 3220
2-Aminoethylbenzene
1-Phenyl-2-amino-athan [German]
.beta.-Phenethylamine
NSC 10811
phenethyl-amine
.beta.-Aminoethylbenzene
HSDB 3526
1tnj
1utm
1uto
b-aminoethylbenzene
EINECS 200-574-4
UNII-327C7L2BXQ
MFCD00008184
BRN 0507488
327C7L2BXQ
omega-Phenylethylamine
CHEBI:18397
AI3-03117
.beta.-Phenylaethylamin
.omega.-Phenylethylamine
NSC-10811
CHEMBL610
DTXSID5058773
EC 200-574-4
PHENETHYLAMINE, HYDROCHLORIDE
benzene, (2-aminoethyl)-
beta-phenylaethylamin (german)
phenethyl amine
1-Phenyl-2-amino-athan (GERMAN)
.beta.-Phenylathylaminhydrochlorid
SMR000471837
PHEA
phenethylamin
phenethylarnine
b-phenethylamine
N-phenethylamine
Phenylethyl amine
b-phenylaethylamin
benzene-ethanamine
2-penylethylamine
beta Phenethylamine
2-phenylethaneamine
2-phenylethariamine
2-phenyl-ethylamine
2-phenyl-Ethanamine
2-Phenylethyl amine
N-Benzylmethyl-amine
14C-phenylethylamine
(2-phenylethyl)amine
2-(phenyl)ethylamine
2-Phenylethanamine #
2-(aminoethyl)benzene
Phenethylamine, 99%
Phenethylamine, .beta.
2-Phenethylamine, liquid
Phenethylamine, >=99%
1-Phenyl-2-amino-aethan
SCHEMBL968
bmse000377
PHENETHYLAMINE [MI]
b-phenylaethylamin (german)
WLN: Z2R
PHENETHYLAMINE [FHFI]
MLS001066395
MLS001075768
SCHEMBL330324
GTPL2144
PHENETHYLAMINE [WHO-DD]
DTXCID3044172
BDBM10758
2-PHENYLETHYLAMINE [HSDB]
HMS2267J14
HMS3886K21
NSC10811
STR01455
s5347
STL264196
2-Phenethylamine, analytical standard
2-phenylethanamine (ACD/Name 4.0)
2-phenylethylamine (ACD/Name 4.0)
AKOS000119084
CCG-266078
CS-W011199
DB04325
HY-W010483
NCGC00163366-01
NCGC00163366-04
DB-002852
NS00010853
P0085
C05332
D78532
Q407411
Phenethylamine, purified by redistillation, >=99.5%
60BC7032-7CEC-4B97-B365-EA6E475E6E3C
InChI=1/C8H11N/c9-7-6-8-4-2-1-3-5-8/h1-5H,6-7,9H
200-574-4