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Phenelzine dihydrochloride

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Identification
Molecular formula
C8H12N2 · 2HCl
CAS number
156-05-8
IUPAC name
2-phenylethylhydrazine;dihydrochloride
State
State

At room temperature, phenelzine dihydrochloride is in a solid state and is commonly found as a crystalline powder.

Melting point (Celsius)
131.00
Melting point (Kelvin)
404.15
Boiling point (Celsius)
146.30
Boiling point (Kelvin)
419.45
General information
Molecular weight
246.18g/mol
Molar mass
171.2470g/mol
Density
1.1639g/cm3
Appearence

Phenelzine dihydrochloride typically appears as a white to off-white crystalline powder. It is often hygroscopic, meaning it can absorb moisture from the environment, which may affect its appearance over time.

Comment on solubility

Solubility of 2-phenylethylhydrazine dihydrochloride

When examining the solubility of 2-phenylethylhydrazine dihydrochloride, it's important to consider both its ionic nature and the effects of hydrophilicity. This compound, being a dihydrochloride salt, generally exhibits higher solubility in polar solvents due to the presence of the chloride ions.

Key Points on Solubility:

  • The ionic character contributes to its solubility in water; ionic compounds typically dissolve well in aqueous solutions.
  • It may show limited solubility in non-polar solvents, such as hydrocarbons, due to unfavorable interactions.
  • Temperature can influence solubility; usually, higher temperatures enhance the solubility of many salts.

In summary, 2-phenylethylhydrazine dihydrochloride is likely to be soluble in water and other polar solvents while being considerably less soluble in non-polar environments. This behavior reflects typical patterns observed in compounds with similar functional groups and ionic characteristics.

Interesting facts

Interesting Facts About 2-Phenylethylhydrazine Dihydrochloride

2-Phenylethylhydrazine dihydrochloride is a fascinating compound that plays a notable role in both organic synthesis and medicinal chemistry. Here are some intriguing points about this compound:

  • Pharmacological Interest: This compound is often researched for its potential therapeutic applications, particularly in the realm of neuropharmacology. It has shown promise in studies related to mood enhancement and neuroprotection.
  • Hydrazine Derivative: As a hydrazine derivative, it features a unique nitrogen-nitrogen bond that is significant in many biochemical reactions. Such compounds are often involved in the synthesis of various pharmaceuticals.
  • Reactivity: Due to its hydrazine functionality, it exhibits interesting reactivity patterns. This includes potential reactions with carbonyl compounds to form hydrazones, which are valuable intermediates in organic chemistry.
  • Research Applications: This compound is frequently employed in the synthesis of more complex molecules, including those used to produce anti-cancer agents. Its structural properties make it a useful building block in drug development.
  • Toxicological Profile: Like many hydrazine derivatives, 2-phenylethylhydrazine dihydrochloride requires careful handling due to potential toxicity. It is important for chemists to adhere to safety protocols when working with this substance.

In summary, the study of 2-phenylethylhydrazine dihydrochloride not only showcases the complexities of organic synthesis but also highlights the ongoing journey of medicinal chemistry in discovering new therapeutic agents. As one researcher eloquently stated, "In the world of compounds, each molecule holds the key to potential innovations."

Synonyms
phenethylhydrazine dihydrochloride
USAF LA-10
Phelasin
Phelazine
Phenelzine dihydrochloride
HYDRAZINE, PHENETHYL-, DIHYDROCHLORIDE
2-Phenyl-ethyl hydrazine dihydrochloride
Hydrazine, (2-phenylethyl)-, dihydrochloride
DTXSID70168641
DTXCID6091132
Hydrazine, (2-phenylethyl)-, dihydrochloride (9CI)
835-550-8
16904-30-6
1-(2-phenylethyl)hydrazine dihydrochloride
MFCD01722349
2-phenylethylhydrazine;dihydrochloride
(2-phenylethyl)hydrazine dihydrochloride
phenethylhydrazinedihydrochloride
orb1302267
SCHEMBL2786042
AC4670
AKOS030627361
BS-52201
SY048081
EN300-41855
Z927192062