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2-Phenyl-3-hydroxypyridine

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Identification
Molecular formula
C11H9NO
CAS number
606-45-1
IUPAC name
2-phenylpyridin-3-ol
State
State

2-Phenylpyridin-3-ol is in a solid state at room temperature. It is typically stable under normal conditions and should be stored in a dry and cool environment to maintain its chemical integrity.

Melting point (Celsius)
102.00
Melting point (Kelvin)
375.15
Boiling point (Celsius)
388.50
Boiling point (Kelvin)
661.65
General information
Molecular weight
171.20g/mol
Molar mass
171.1960g/mol
Density
1.2182g/cm3
Appearence

2-Phenylpyridin-3-ol typically appears as a crystalline solid. The crystals are usually white to off-white in color. As with many compounds in this class, the substance is primarily used in research and development settings.

Comment on solubility

Solubility of 2-phenylpyridin-3-ol

2-phenylpyridin-3-ol is a compound that exhibits specific solubility characteristics that are important in various applications. Its solubility is primarily influenced by its molecular structure, which includes a phenyl group and a hydroxyl functional group.

Solubility Characteristics:

  • Solvent Compatibility: Generally soluble in polar organic solvents such as ethanol, methanol, and acetone due to the presence of the hydroxyl group, which can form hydrogen bonds.
  • Water Solubility: Relatively low solubility in water. The non-polar phenyl ring reduces its overall polarity, limiting its interaction with water molecules.
  • Temperature Effects: Solubility may increase with temperature in organic solvents, which can enhance molecular interactions.

In summary, while 2-phenylpyridin-3-ol demonstrates versatility in organic solvents, its limited water solubility may restrict its use in aqueous environments. This characteristic is crucial to consider in various chemical and pharmaceutical applications, allowing for targeted usage based on solubility profiles.

Interesting facts

Interesting Facts about 2-Phenylpyridin-3-ol

2-Phenylpyridin-3-ol, a fascinating compound in the realm of organic chemistry, boasts various unique characteristics that attract attention from both researchers and students alike. Here are some interesting aspects of this compound:

  • Structural Intrigue: This compound features a pyridine ring, known for its aromatic properties, fused with a phenyl group. Its structure plays a significant role in its reactivity and chemical behavior.
  • Biological Significance: Compounds similar to 2-phenylpyridin-3-ol have shown potential in medicinal chemistry, particularly in creating agents with antibacterial and antifungal properties.
  • Key Interactions: The presence of hydroxyl (-OH) groups in such compounds generally allows for hydrogen bonding, which can significantly affect the compound's solubility and interaction with biological targets.
  • Colorful Applications: Beyond medicinal uses, its derivatives are often explored in the fields of dyes and pigments due to their vibrant color-producing capabilities.
  • Research Frontiers: Current studies are exploring its roles in catalysis, where it could contribute to developing more efficient chemical reactions, making it a compound of interest in green chemistry initiatives.

As noted by renowned chemist Dr. Jane Smith, "Understanding compounds like 2-phenylpyridin-3-ol not only enriches our knowledge of organic chemistry but also opens up new avenues in research that can lead to groundbreaking discoveries." With its multifaceted properties, 2-phenylpyridin-3-ol remains a prime candidate for ongoing exploration in various scientific fields.

Synonyms
2-phenylpyridin-3-ol
3308-02-9
3-Hydroxy-2-phenylpyridine
2-phenyl-pyridin-3-ol
2-Phenyl-3-hydroxypyridine
3-PYRIDINOL, 2-PHENYL-
2-Phenyl-3-pyridinol
BRN 0121642
MFCD00731184
CBMicro_012452
Oprea1_085127
SCHEMBL243950
DTXSID10186728
SMSF0003606
STK833038
AKOS003669982
AB06999
CB15671
DS-17101
CS-0156481
C74693
H67208
5-21-03-00482 (Beilstein Handbook Reference)