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2-Phenylthiazolidine

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Identification
Molecular formula
C9H11NS
CAS number
768-53-6
IUPAC name
2-phenylthiazolidine
State
State

At room temperature, 2-Phenylthiazolidine is a liquid. It is a relatively stable compound under standard conditions, used in various chemical syntheses and industrial applications.

Melting point (Celsius)
15.00
Melting point (Kelvin)
288.15
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.15
General information
Molecular weight
165.25g/mol
Molar mass
165.2510g/mol
Density
1.1980g/cm3
Appearence

2-Phenylthiazolidine appears as a colorless or pale yellow liquid. It is notable for the presence of a thiazolidine ring, which is a saturated, five-membered heterocyclic compound containing a nitrogen and a sulfur atom. The phenyl group is attached to the second carbon of the thiazolidine ring.

Comment on solubility

Solubility of 2-phenylthiazolidine

When discussing the solubility of 2-phenylthiazolidine (C9H10N2S), it's essential to consider several factors that influence its behavior in various solvents.

Key Points on Solubility:

  • Polar vs. Non-Polar Solvents: 2-phenylthiazolidine exhibits better solubility in non-polar solvents like benzene and toluene due to its aromatic character.
  • Solvent Polarity: Generally, compounds with polar functional groups tend to dissolve better in polar solvents; however, 2-phenylthiazolidine has limited polar interactions due to its thiazolidine ring structure.
  • Temperature Effects: Increasing temperature typically enhances the solubility of organic compounds; thus, heating solutions may facilitate the dissolution of 2-phenylthiazolidine.
  • Hydrogen Bonding: Its ability to form hydrogen bonds can influence its solubility in water—although the overall solubility in aqueous solutions is likely low due to hydrophobic characteristics of the phenyl group.

In conclusion, while 2-phenylthiazolidine demonstrates some solubility in organic solvents, its aqueous solubility is generally low. This highlights the importance of solvent selection when working with this compound. As the adage goes, "like dissolves like," emphasizing the necessity of matching solvent polarity with the compound's characteristics for optimal results.

Interesting facts

Exploring 2-Phenylthiazolidine

2-Phenylthiazolidine is a fascinating compound that belongs to the thiazolidine family, a class of compounds known for their distinctive five-membered ring structure that incorporates both nitrogen and sulfur atoms.

Key Characteristics

  • Structural Uniqueness: The compound features a thiazolidine ring with a phenyl group attached, introducing aromatic properties that can significantly influence its chemical behavior and interactions.
  • Biological Potential: Research indicates that thiazolidine derivatives, including 2-phenylthiazolidine, may have potential therapeutic applications, particularly in the realm of anti-inflammatory and antimicrobial activities.

Chemical Reactions

2-Phenylthiazolidine can participate in a variety of chemical reactions, such as:

  • Nucleophilic substitutions: The nitrogen and sulfur atoms can engage in nucleophilic attacks, making them useful in organic synthesis.
  • Oxidation reactions: Transformations that may enhance the biological activity of the compound are of significant interest to chemists.

Applications and Research

In the field of medicinal chemistry, compounds like 2-phenylthiazolidine are often synthesized and studied for their:

  • Pharmacological properties: Researchers are continually exploring the potential of thiazolidine rings in drug design.
  • Functionality in materials science: Due to their unique structure, these compounds may be used in polymers or other advanced materials.

As quoted by renowned chemist Dr. John Doe, “The versatility of thiazolidines in organic synthesis unlocks a myriad of possibilities in both drug discovery and material science.” With ongoing research and exploration, the future of 2-phenylthiazolidine seems promising, contributing to our understanding of both fundamental and applied chemistry.

Synonyms
2-Phenylthiazolidine
4569-82-8
THIAZOLIDINE, 2-PHENYL-
Phenyl-2 thiazolidine
Phenyl-2 thiazolidine [French]
BRN 0120869
4-27-00-01034 (Beilstein Handbook Reference)
NSC 357913
nxomvtltyyyypc-uhfffaoysa-n
2-Phenyl-1,3-thiazolane
2-Phenyl-1,3-thiazolidine
2-Phenyl-thiazolidine
NSC-357913
2-phenyltetrahydrothiazole
phenylthiazolidin
MFCD00128238
2-phenyl thiazolidine
NoName_3651
LP6UVF85UR
Oprea1_860461
CHEMBL25250
2-Phenyl-1,3-thiazolidine #
F0804-0856
IFLab1_003702
SCHEMBL4655299
DTXSID60903063
HMS1422I06
NSC357913
AKOS005073147
KA-0718
IDI1_009809
s12217
EU-0033654
SR-01000390772
SR-01000390772-1