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Phenoxybenzamine hydrochloride

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Identification
Molecular formula
C18H24ClNO2
CAS number
63-92-3
IUPAC name
2-piperidin-1-ium-1-ylethyl N-(2-phenoxyphenyl)carbamate;chloride
State
State

At room temperature, phenoxybenzamine hydrochloride is typically in a solid state.

Melting point (Celsius)
136.00
Melting point (Kelvin)
409.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
303.81g/mol
Molar mass
303.8090g/mol
Density
1.2100g/cm3
Appearence

Phenoxybenzamine hydrochloride appears as a white or off-white crystalline powder. It is typically odorless and is used in powder form for pharmaceutical preparations.

Comment on solubility

Solubility of 2-piperidin-1-ium-1-ylethyl N-(2-phenoxyphenyl)carbamate;chloride

The solubility of 2-piperidin-1-ium-1-ylethyl N-(2-phenoxyphenyl)carbamate;chloride can be quite intriguing due to its complex structure. Generally, the solubility of a compound is influenced by several factors:

  • Polarity: This compound contains both polar and non-polar components. The presence of the chloride group usually increases solubility in polar solvents (like water), while the phenoxy group can enhance solubility in non-polar solvents.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds with solvents can significantly affect its solubility. The presence of the amine group on the piperidine structure may facilitate interactions with water.
  • Ionization: As it exists in a salt form (chloride), the ionized version may enhance its solubility in aqueous solutions considerably.

Based on these factors, the compound is likely:

  • Soluble in warm water or other polar solvents due to its ionic chloride:
  • Exhibiting moderate solubility in non-polar solvents due to the large aromatic system.

However, practical solubility testing is recommended to determine the exact solubility in various solvents, as theoretical predictions can vary based on formulation and environmental conditions.

Interesting facts

Interesting Facts About 2-piperidin-1-ium-1-ylethyl N-(2-phenoxyphenyl)carbamate; chloride

This compound is part of a fascinating class of chemicals known as carbamates, which are widely used in various fields of science and industry. Here's why it stands out:

  • Biological Activity: Compounds like this one often exhibit significant biological properties, making them valuable in pharmaceutical research. They can potentially act as inhibitors or modulators of biological pathways.
  • Structure-Activity Relationships: The presence of the piperidin-1-ium ring confers unique properties that influence receptor binding and enzyme interactions. This compound can shed light on how subtle changes in structure affect activity.
  • Applications in Agriculture: Carbamates are known for their use in pesticides and herbicides, making them crucial in modern agricultural practices. Understanding compounds like this one can lead to the development of safer and more effective agricultural chemicals.
  • Research Potential: Ongoing studies explore the use of similar compounds in developing treatments for various diseases, including cancer and neurological disorders.
  • Chemical Versatility: The specific functional groups in this compound lend it a wide range of reactivity, enabling chemists to modify it for different applications, from symbiotic agents in organic synthesis to protective agents in materials science.

As with many chemical compounds, the potential innovations derived from understanding and manipulating 2-piperidin-1-ium-1-ylethyl N-(2-phenoxyphenyl)carbamate; chloride may lead to breakthroughs in medicine and sustainable agriculture. As noted in the words of famed chemist Linus Pauling, “Science is a search for the simplest laws that govern the universe.” Exploring compounds like this is a step toward understanding complexity in nature.

Synonyms
o-Phenoxycarbanilic acid 2-piperidinoethyl ester hydrochloride
19447-99-5
KP 50
CARBANILIC ACID, o-PHENOXY-, 2-PIPERIDINOETHYL ESTER, HYDROCHLORIDE