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Chlorphenamine maleate

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Identification
Molecular formula
C16H19ClN2O•Cl
CAS number
132-22-9
IUPAC name
2-piperidin-1-ium-1-ylethyl N-(3-chloro-4-methyl-phenyl)carbamate;chloride
State
State

Chlorphenamine maleate is typically encountered in solid form at room temperature. It is stable under normal conditions and is often marketed in tablet or syrup forms for pharmaceutical applications.

Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
218.30
Boiling point (Kelvin)
491.45
General information
Molecular weight
274.75g/mol
Molar mass
274.7520g/mol
Density
1.1500g/cm3
Appearence

Chlorphenamine maleate appears as a white to off-white crystalline powder. This compound is typically odorless and has a bitter taste. It is highly soluble in water and slightly soluble in alcohol.

Comment on solubility

Solubility of 2-piperidin-1-ium-1-ylethyl N-(3-chloro-4-methyl-phenyl)carbamate;chloride

The solubility of 2-piperidin-1-ium-1-ylethyl N-(3-chloro-4-methyl-phenyl)carbamate;chloride is an intriguing aspect, as it encompasses various factors influencing its behavior in different environments. To distill the essentials:

  • Water Solubility: This compound is expected to have limited solubility in water due to its complex structure, which combines hydrophilic and hydrophobic regions.
  • Solvent Compatibility: Solubility may improve in organic solvents such as ethanol or acetone, owing to the presence of the aromatic phenyl group that better interacts with non-polar environments.
  • pH Dependence: The solubility might also be influenced by the pH of the solution, as protonation of the piperidine ring could enhance its solubility in aqueous solutions.
  • Temperature Effects: As with many chemical compounds, increases in temperature could enhance solubility due to increased kinetic energy and disruption of solute-solvent interactions.

In summary, the solubility behavior of this compound is multifaceted, influenced by various chemical and physical properties. Understanding these aspects can guide researchers in optimizing conditions for applications in both experimental and industrial settings. As with many complex compounds, solid solubility data may require study under specific conditions to fully appreciate its applications.

Interesting facts

Interesting Facts About 2-Piperidin-1-ium-1-ylethyl N-(3-chloro-4-methyl-phenyl)carbamate; Chloride

The compound 2-piperidin-1-ium-1-ylethyl N-(3-chloro-4-methyl-phenyl)carbamate; chloride represents a fascinating avenue of research, primarily within the fields of chemistry and pharmacology. Here are some noteworthy aspects:

  • Pharmacological Potential: This compound's unique structure suggests potential activity as a therapeutic agent. The presence of the piperidinium group often implies interactions with biological systems, particularly as a quaternary ammonium compound.
  • Mechanism of Action: Compounds like this one may act as inhibitors or modulators of specific enzymes or receptors, making them valuable in drug design and discovery.
  • Synthetic Routes: The synthesis of this compound can involve various methods of organic chemistry, including nucleophilic substitutions and coupling reactions, which are fundamental techniques in creating complex molecules.
  • Structure-Activity Relationship (SAR): Investigating how the structural components influence biological activity can provide insights into optimizing compounds for medicinal purposes. Each functional group may contribute uniquely to the overall pharmacokinetics and pharmacodynamics.

Moreover, the presence of the 3-chloro-4-methylphenyl moiety adds to its unique profile, suggesting interesting interactions due to its electron-withdrawing properties. Quotes from research suggest, "Understanding the intricate details of such compounds can unlock new therapies and improve existing treatments."

Overall, as we delve deeper into the study of 2-piperidin-1-ium-1-ylethyl N-(3-chloro-4-methyl-phenyl)carbamate; chloride, we discover its potential not just as a chemical entity but as a promising candidate in the realm of drug development. With ongoing research, it might lead to breakthroughs that can significantly impact human health and medical therapies.

Synonyms
3-Chloro-4-methylcarbanilic acid 2-piperidinoethyl ester hydrochloride
20224-22-0
K 446
CARBANILIC ACID, 3-CHLORO-4-METHYL-, 2-PIPERIDINOETHYL ESTER, HYDROCHLORIDE