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Phenoxybenzamine hydrochloride

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Identification
Molecular formula
C18H23ClN2O3
CAS number
63-92-3
IUPAC name
2-piperidin-1-ium-1-ylethyl N-(3-phenoxyphenyl)carbamate;chloride
State
State

At room temperature, phenoxybenzamine hydrochloride exists as a solid. Due to its hygroscopic nature, it needs to be stored in controlled conditions to prevent moisture uptake.

Melting point (Celsius)
137.00
Melting point (Kelvin)
410.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
396.88g/mol
Molar mass
396.3290g/mol
Density
1.2000g/cm3
Appearence

Phenoxybenzamine hydrochloride is a white to off-white crystalline powder. It is odorless or may have a faint characteristic odor. This compound is hygroscopic, meaning it can absorb moisture from the environment.

Comment on solubility

Solubility of 2-piperidin-1-ium-1-ylethyl N-(3-phenoxyphenyl)carbamate;chloride

The solubility of 2-piperidin-1-ium-1-ylethyl N-(3-phenoxyphenyl)carbamate;chloride is an intriguing aspect that plays a critical role in its applications and behavior in various environments. This compound exhibits solubility characteristics that can be summarized as follows:

  • Water Solubility: While the presence of the chloride ion may enhance its solubility in aqueous environments, the overall solubility can vary significantly based on temperature and pH.
  • Organic Solvents: Due to the phenoxy and piperidinic groups, the compound is likely to dissolve well in polar organic solvents such as methanol and ethanol, while showing limited solubility in non-polar solvents.
  • Temperature Dependence: Like many ionic compounds, solubility may increase with temperature; thus, understanding its behavior under different thermal conditions is essential for practical applications.

In conclusion, the solubility of this compound can be influenced by various factors including:

  1. Nature of the solvent
  2. Temperature
  3. pH of the solution

“Understanding solubility enhances our capacity to predict the behavior of compounds in real-world scenarios.” Therefore, careful consideration of these factors is necessary when working with 2-piperidin-1-ium-1-ylethyl N-(3-phenoxyphenyl)carbamate;chloride.

Interesting facts

Interesting Facts about 2-piperidin-1-ium-1-ylethyl N-(3-phenoxyphenyl)carbamate;chloride

This intriguing compound, known as a quaternary ammonium salt, possesses a unique structure that combines functionality with synthetic versatility. Here are some fascinating aspects of this compound:

  • Dual Activity: The compound's structure allows it to participate in various chemical reactions, making it a valuable building block in organic synthesis.
  • Biological Significance: Quaternary ammonium compounds are widely recognized for their biological activity, including antimicrobial and antifungal properties, which can make them excellent candidates for pharmaceutical applications.
  • Versatile Applications: This compound can be utilized in various fields such as medicinal chemistry, agricultural chemistry, and material science thanks to its functional groups.
  • Enhanced Stability: The presence of the piperidinium group contributes to the compound's stability and solubility in different solvents, which is critical for its use in laboratory settings.
  • Potential in Drug Delivery: Due to their amphiphilic nature, compounds like this can be engineered to enhance the delivery of drugs, improving therapeutic outcomes.

As one dives deeper into the chemistry of this compound, the functional diversity and potential applications in modern science become increasingly apparent, making it a noteworthy subject of study for both chemists and pharmacologists alike. Moreover, the ongoing research into such compounds continues to inspire innovative uses and developments in various industries.

Synonyms
m-Phenoxycarbanilic acid 2-piperidinoethyl ester hydrochloride
19448-00-1
KP 51
CARBANILIC ACID, m-PHENOXY-, 2-PIPERIDINOETHYL ESTER, HYDROCHLORIDE