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Trimebutine maleate

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Identification
Molecular formula
C22H27NO5
CAS number
34140-59-5
IUPAC name
2-(piperidin-1-ium-1-ylmethyl)-3,4-dihydro-2H-dibenzofuran-1-one;chloride
State
State

Trimebutine maleate is typically found in a solid state at room temperature. As a crystalline powder, it maintains its structure under standard conditions and is non-volatile.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.15
Boiling point (Celsius)
298.00
Boiling point (Kelvin)
571.15
General information
Molecular weight
387.91g/mol
Molar mass
387.9060g/mol
Density
1.2909g/cm3
Appearence

Trimebutine maleate appears as a white or almost white crystalline powder. It is odorless and has a slightly bitter taste. The powder is relatively stable when exposed to air and light.

Comment on solubility

Solubility of 2-(piperidin-1-ium-1-ylmethyl)-3,4-dihydro-2H-dibenzofuran-1-one;chloride

The solubility characteristics of the compound 2-(piperidin-1-ium-1-ylmethyl)-3,4-dihydro-2H-dibenzofuran-1-one;chloride can be quite intriguing. This compound, featuring a piperidinium ion, suggests that it may exhibit a tendency towards dissolution in polar solvents due to its ionic nature. Here are several key points regarding its solubility:

  • Solvent Preference: It is likely to be more soluble in water and other polar solvents compared to non-polar solvents.
  • Ionic Interaction: The presence of the chloride ion can enhance solubility in aqueous solutions due to interactions with water molecules.
  • Piperidinium Structure: The piperidin-1-ium portion of the molecule contributes to its ionic characteristics, potentially increasing solubility in aqueous environments.

While specific solubility values may be influenced by temperature and concentration, it is safe to postulate that the compound will exhibit reasonably high solubility in polar solvents, which is a favorable characteristic for applications in biological and chemical systems. Understanding the solubility behavior of such compounds is crucial for their effective use in various fields.

Interesting facts

Interesting Facts about 2-(piperidin-1-ium-1-ylmethyl)-3,4-dihydro-2H-dibenzofuran-1-one;chloride

This compound is a fascinating example of chemical diversity and complexity, showcasing the interplay between organic chemistry and pharmacology. Here are a few key points that highlight its significance:

  • Structural Complexity: The presence of a piperidinium ring coupled with a dibenzofuran core indicates a sophisticated molecular architecture. This complexity can influence the compound's biological activities and interactions with various biological targets.
  • Pharmacological Potential: Compounds similar to this one are often studied for their potential as therapeutic agents. The piperidine framework is known for imparting unique pharmacodynamic properties, making it a vital point of interest in drug discovery.
  • Ionization Behavior: As a chloride salt, this compound can exist in ionized form, which is important for its solubility and bioavailability. Understanding how such compounds behave in biological systems is crucial for medicinal chemistry.
  • Synthetic Relevance: The synthesis of this compound may involve intricate organic reactions, providing insights into synthetic methodology and the development of new chemical reactions.
  • Research Applications: Researchers may utilize this compound to explore its efficacy in various biological assays, potentially discovering new pathways in disease treatment or understanding existing metabolic processes.

In summary, 2-(piperidin-1-ium-1-ylmethyl)-3,4-dihydro-2H-dibenzofuran-1-one;chloride serves as a prime example of how structural intricacies in molecular design can translate into valuable insights for scientific research and application. Its potential roles in pharmacology and synthesis provide a rich ground for examination and discovery.

Synonyms
L 5360
2-(Piperidinomethyl)-3,4-dihydro-1(2H)-dibenzofuranone hydrochloride
1(2H)-DIBENZOFURANONE, 3,4-DIHYDRO-2-(PIPERIDINOMETHYL)-, HYDROCHLORIDE
Chlorhydrate de l' oxo-1 piperidinomethyl-2 tetrahydro-1,2,3,4 dibenzofuranne [French]
24484-63-7
Chlorhydrate de l' oxo-1 piperidinomethyl-2 tetrahydro-1,2,3,4 dibenzofuranne
RefChem:211475