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2-propylbenzimidazole

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Identification
Molecular formula
C10H12N2
CAS number
3183-68-0
IUPAC name
2-propyl-1H-benzimidazole
State
State

At room temperature, 2-propylbenzimidazole is typically found as a solid. It is stable under normal conditions and does not readily vaporize.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
160.21g/mol
Molar mass
160.2140g/mol
Density
1.1000g/cm3
Appearence

2-propylbenzimidazole appears as a white to off-white crystalline solid. Its appearance may vary slightly depending on purity and particle size.

Comment on solubility

Solubility of 2-propyl-1H-benzimidazole

The solubility of 2-propyl-1H-benzimidazole in various solvents presents an intriguing aspect of its chemical behavior. Understanding its solubility can help in applications such as pharmaceuticals and material sciences.

Key Points about Solubility:

  • Solvent Interaction: This compound is generally more soluble in organic solvents, indicating its non-polar character and limited solubility in polar solvents like water.
  • Influence of Temperature: Solubility may increase with temperature, as is typical for many organic compounds.
  • Impurities Effect: The presence of impurities or co-solvents can significantly impact the solubility behavior of 2-propyl-1H-benzimidazole.

In summary, the solubility of 2-propyl-1H-benzimidazole is an essential characteristic to consider for practical applications, especially in fields that require the manipulation of solubility properties in a variety of environments. It emphasizes the significance of solvation dynamics and solvent compatibility in chemical interactions.

Interesting facts

Exploring 2-Propyl-1H-benzimidazole

2-Propyl-1H-benzimidazole is a fascinating compound that belongs to the class of benzimidazole derivatives, which have garnered attention due to their diverse biological activities. This compound features a unique structure that is often highlighted for its potential applications in various fields.

Key Highlights:

  • Biological Significance: Compounds in the benzimidazole family, including 2-propyl-1H-benzimidazole, are famous for their therapeutic effects. They are often studied for their anti-inflammatory, antimicrobial, and anticancer properties.
  • Pharmaceutical Applications: Some benzimidazole derivatives are used in pharmaceuticals, such as the widely known anti-parasitic drug, mebendazole. The varied activities of benzimidazole derivatives make them prime candidates for drug development.
  • Mechanistic Insights: The mechanism of action often involves the targeting of microtubules or DNA-related processes, resulting in impactful biological responses.
  • Research Advances: Ongoing research in medicinal chemistry continues to explore new derivatives and their specific functionalities, making this a dynamic area of study.

As a student or scientist in the field of chemistry, one can appreciate the *interdisciplinary nature* of 2-propyl-1H-benzimidazole. It bridges the gap between organic chemistry and pharmacology, illustrating how a compound's structure directly influences its biological activity. The pursuit of understanding and synthesizing such compounds can lead to the development of novel treatments that could revolutionize healthcare.

In short, 2-propyl-1H-benzimidazole stands out not only for its chemical uniqueness but also for its potential impact on human health, making it a compound worthy of attention in scientific research.

Synonyms
2-Propylbenzimidazole
2-Propyl-1H-benzimidazole
5465-29-2
2-propyl-1H-benzo[d]imidazole
1H-Benzimidazole, 2-propyl-
2-propyl-1H-1,3-benzodiazole
BENZIMIDAZOLE, 2-PROPYL-
MFCD00087477
ZAS7IXN9P8
CHEMBL348508
NSC-28962
NSC-40172
NSC 40172
NSC 28962
1H-Benzimidazole, 2-propyl- (9CI)
2-Propyl-1H-benzoimidazole
BRN 0118511
Enamine_005118
UNII-ZAS7IXN9P8
5-23-06-00498 (Beilstein Handbook Reference)
MLS000564234
2-Propyl-1H-benzimidazole #
SCHEMBL612507
F0293-0118
DTXSID30203108
HMS1408I14
HMS2411G15
ALBB-016087
BCP26962
NSC28962
NSC40172
BDBM50404849
STL168975
AKOS000271113
CS-W002355
DS-0770
FS-2307
IDI1_007705
NCGC00246151-01
SMR000151838
SY015986
DB-025928
EN300-02976
Z55692902
InChI=1/C10H12N2/c1-2-5-10-11-8-6-3-4-7-9(8)12-10/h3-4,6-7H,2,5H2,1H3,(H,11,12