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2-Propylpiperidine

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Identification
Molecular formula
C8H17N
CAS number
622-58-2
IUPAC name
2-propylpiperidine
State
State

At room temperature, 2-propylpiperidine is a colorless liquid. It is stable under normal conditions and can be used in laboratory settings.

Melting point (Celsius)
-70.00
Melting point (Kelvin)
203.15
Boiling point (Celsius)
161.50
Boiling point (Kelvin)
434.65
General information
Molecular weight
127.22g/mol
Molar mass
127.2220g/mol
Density
0.8760g/cm3
Appearence

2-Propylpiperidine typically appears as a colorless liquid. It is an organic compound that may exhibit a slight amine-like odor, which is common to piperidinyl derivatives. Its appearance can vary slightly with impurities or when oxidized.

Comment on solubility

Solubility of 2-propylpiperidine

2-propylpiperidine, with its unique structure, exhibits interesting solubility characteristics. Understanding the solubility of this compound can help in various applications and synthesis processes.


Key Solubility Insights:

  • Solvent Interaction: 2-propylpiperidine is generally soluble in organic solvents such as ethanol, methanol, and dichloromethane, making it suitable for use in organic chemistry protocols.
  • Water Solubility: This compound is weakly soluble in water due to the presence of the hydrophobic propyl group, which limits its interaction with polar water molecules.
  • Temperature Effects: Solubility can be influenced by temperature; increasing temperatures often enhance the solubility of organic compounds in solvents.

As a result, while 2-propylpiperidine may not be highly soluble in water, it finds extensive utility in non-aqueous environments, showcasing the profound impact of solubility on the behavior and applications of chemical compounds.

Interesting facts

Interesting Facts about 2-Propylpiperidine

2-Propylpiperidine is a fascinating compound in the realm of organic chemistry, primarily due to its unique structure and properties. As a member of the piperidine family, this compound features a six-membered ring containing nitrogen, which significantly influences its chemical behavior and potential applications.

Key Characteristics

  • Structure: The piperidine ring in 2-propylpiperidine is substituted with a propyl group, resulting in distinct steric effects that can impact reactivity.
  • Reactivity: This compound can undergo various reactions typical of amines, including acylation and alkylation processes, making it a versatile intermediate in synthetic chemistry.

Applications

2-Propylpiperidine has gained attention in several fields, including:

  • Synthetic Chemistry: Utilized in the synthesis of pharmaceuticals and agrochemicals, the compound serves as a building block for more complex molecules.
  • Drug Development: Its structural features are often explored to create compounds with potential biological activity, particularly in the realm of neurology.
  • Analytical Chemistry: Used in the development of various analytical techniques, allowing chemists to study reaction mechanisms and properties of other compounds.

Historical Context

The study of piperidine derivatives like 2-propylpiperidine has a rich history, originating from the natural sources of piperine found in black pepper. Chemists have since synthesized numerous derivatives impacting various industries.

Fascinating Trivia

Did you know? The nitrogen atom in piperidine can impart basic properties to the compound, enabling it to act as a nucleophile in organic reactions. This characteristic is crucial for the formation of complex structures in pharmaceutical chemistry.

Understanding 2-propylpiperidine's properties and applications not only reflects the intricacies of organic chemistry but also highlights the endless possibilities for innovation in drug design and other practical applications.

Synonyms
2-Propylpiperidine
3238-60-6
2-N-propylpiperidine
CONIINE
dl-Coniine
(+/-)-Coniine
2-Propyl-piperidine
d-Conicine
Cicutin
Coniin
MFCD00056022
10388-95-1
DTXSID3046821
04R53ZF48T
NCGC00181040-01
alpha-Conine
DTXCID1026821
piperidine, 2-propyl-
CAS-3238-60-6
(+-)-Coniine
CONIINE, D/L-(RG)
(1)-2-Propylpiperidine
Conicin
UNII-04R53ZF48T
EINECS 221-801-3
CONIINE, DL-
piperidine, 2-n-propyl-
SCHEMBL96923
MLS004712093
CHEMBL21867
CONIINE, (+/-)-
CHEBI:229941
Piperidine, 2-propyl-, (+-)-
ALBB-011873
BCP24768
BCP30484
Tox21_112688
BBL022356
MSK158026
STK693929
( inverted exclamation markA)-Coniine
(+/-)-Coniine, >=98%, liquid
AKOS001476535
Tox21_112688_1
HY-121229A
SB42981
NCGC00181040-02
MS-20416
SMR001562138
1ST158026
DB-006213
PIPERIDINE, 2-PROPYL-, (+/-)-
CS-0128773
NS00008611
EN300-124811
F16896
Q27247670
F8881-6048
Cicutin; Cicutine; Conicine;(S)-2-Propylpiperidine;(S)-beta-Propylpiperidine