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Nicotinic acid benzoyloxy ester

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Identification
Molecular formula
C13H9NO4
CAS number
5024-30-4
IUPAC name
2-(pyridine-3-carbonyloxy)benzoic acid
State
State

At room temperature, it is in a solid state.

Melting point (Celsius)
216.00
Melting point (Kelvin)
489.15
Boiling point (Celsius)
623.80
Boiling point (Kelvin)
896.95
General information
Molecular weight
229.21g/mol
Molar mass
229.2060g/mol
Density
1.3100g/cm3
Appearence

It is typically a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-(pyridine-3-carbonyloxy)benzoic acid

2-(pyridine-3-carbonyloxy)benzoic acid is a fascinating compound that exhibits unique solubility characteristics. As a derivative of both aromatic acids and pyridine, its solubility can be influenced by several factors:

  • Polarity: Due to the presence of both hydrophobic aromatic rings and polar functional groups, this compound demonstrates a variable solubility profile in different solvents.
  • Solvent Interaction: It is more soluble in polar solvents such as ethanol and dimethyl sulfoxide (DMSO), where intermolecular hydrogen bonding can occur.
  • pH Dependency: The solubility may also be affected by the pH of the medium, as the carboxylic acid group may ionize, enhancing solubility in basic conditions.

In summary, the solubility of 2-(pyridine-3-carbonyloxy)benzoic acid can be described as:

  1. Soluble in polar organic solvents.
  2. Less soluble in non-polar solvents like hexane.
  3. Dependent on the pH of the surrounding environment.

The solubility behavior makes 2-(pyridine-3-carbonyloxy)benzoic acid particularly intriguing for various chemical applications, where understanding these properties can lead to innovative uses in pharmaceuticals and organic synthesis.

Interesting facts

Interesting Facts About 2-(pyridine-3-carbonyloxy)benzoic Acid

2-(pyridine-3-carbonyloxy)benzoic acid is a fascinating compound that merges the structural features of benzoic acid and pyridine, yielding an array of intriguing properties and potential applications. Here are some highlights:

  • Biological Significance: This compound is often investigated for its biological activities, particularly its potential as an anti-inflammatory and analgesic agent. The presence of the pyridine ring can enhance its interaction with biological targets.

  • Versatile Derivative: The carboxylic acid functional group in the structure allows for versatile derivatives to be synthesized, opening doors to numerous catalytic and pharmaceutical applications.

  • Research in Drug Development: Scientists are exploring derivatives of this compound in drug development, especially in relation to cancer treatment, where the unique structure can be tailored to inhibit specific biological pathways.

  • Role in Organic Synthesis: As a building block in organic synthesis, it can facilitate the creation of more complex molecules, showcasing its importance in the development of new materials.

  • Strong Interactions: The ability of this compound to form strong hydrogen bonds is critical, as it plays a role in stabilizing structures in various chemical reactions.

As academic interest continues to grow surrounding 2-(pyridine-3-carbonyloxy)benzoic acid, researchers are optimistic about the contributions this compound can make in medicinal chemistry and materials science. The combination of a heterocyclic structure with traditional aromatic components is quite unique, making each exploration into its properties a promising venture in both theory and practical applications.

Synonyms
Salicylic acid, nicotinate
6629-79-4
3-Pyridinecarboxylic acid, 2-carboxyphenyl ester
UNII-288NV17HC1
288NV17HC1
NSC-57512
DTXSID80216501
NSC 57512
DTXCID40138992
2-(pyridine-3-carbonyloxy)benzoic acid
NICOTINYLSALICYLIC ACID
nicotinatesalicylic acid
SCHEMBL20475060
NSC57512
Q27254287