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MESNA

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Identification
Molecular formula
C6H10N2O4S
CAS number
19767-45-4
IUPAC name
[2-(pyridine-4-carbonyl)hydrazino]methanesulfonic acid
State
State

At room temperature, MESNA is typically a solid.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.00
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.00
General information
Molecular weight
154.21g/mol
Molar mass
154.2100g/mol
Density
1.5000g/cm3
Appearence

MESNA, or [2-(pyridine-4-carbonyl)hydrazino]methanesulfonic acid, generally appears as a white to off-white powder. The compound is crystalline in nature.

Comment on solubility

Solubility of [2-(pyridine-4-carbonyl)hydrazino]methanesulfonic acid

The solubility of [2-(pyridine-4-carbonyl)hydrazino]methanesulfonic acid, with the chemical formula C6H10N2O4S, presents interesting characteristics due to its unique molecular structure and functional groups.

Key Factors Influencing Solubility

  • Polarity: The presence of hydrophilic groups such as the sulfonic acid moiety significantly increases the solubility in polar solvents, especially in water.
  • Hydrogen Bonding: Capable of forming hydrogen bonds, the compound can interact with water molecules, enhancing solubility.
  • pH Dependence: The solubility may vary with pH, displaying higher solubility in acidic conditions due to protonation of the nitrogen atoms.

Expected Solubility Characteristics

In summary, one can make the following predictions about the solubility of [2-(pyridine-4-carbonyl)hydrazino]methanesulfonic acid:

  • Soluble in water, particularly at low pH.
  • May show limited solubility in organic solvents due to its polar nature.
  • Modifications of the solvent system may enhance solubility profiles.

In conclusion, while precise solubility data can vary, understanding the underlying factors offers valuable insights into how this compound behaves in different environments.

Interesting facts

Interesting Facts about 2-(pyridine-4-carbonyl)hydrazino]methanesulfonic acid

2-(pyridine-4-carbonyl)hydrazino]methanesulfonic acid is a fascinating compound with a unique combination of structural features that make it noteworthy in the field of chemistry. Here are some intriguing aspects of this compound:

  • Chemical Structure: This compound features a pyridine ring, which is a six-membered aromatic heterocycle with nitrogen as one of the constituents. This structure is essential in various biological and chemical applications, enhancing the compound's reactivity and interaction with other molecules.
  • Functional Groups: The presence of both hydrazine and methanesulfonic acid functional groups indicates its potential as a versatile reactant in organic synthesis. Hydrazines are known for their role in the formation of azo compounds, while sulfonic acids often serve as excellent leaving groups in reactions.
  • Biological Relevance: Compounds like this one can exhibit significant biological activity. The pyridine moiety is often found in pharmaceuticals and can have effects on nervous system functions, potentially making this compound of interest in medicinal chemistry and drug development.
  • Synthesis and Reactivity: The synthetic pathway to obtain this compound may involve various interesting reactions, such as condensation or coupling reactions. Understanding the reactivity can open doors to creating new derivatives that could have enhanced properties or activities.
  • Applications: This compound could have implications in fields such as:
    • Medicinal Chemistry
    • Pesticide formulation
    • Material Sciences

Overall, 2-(pyridine-4-carbonyl)hydrazino]methanesulfonic acid not only showcases the beauty of organic chemistry through its complex structure but also demonstrates the potential for diverse applications in both synthetic and medicinal chemistry.

Synonyms
Methaniazide
13447-95-5
Isoniazid methanesulfonate
Metaniazida
Methaniazide [INN]
[2-(pyridine-4-carbonyl)hydrazinyl]methanesulfonic acid
GN8S7ZES0F
Methaniazide (INN)
Metaniazide
Isonicotinic acid 2-(sulfomethyl)hydrazine
Methaniazidum
Metaniazide [DCIT]
NCGC00181167-01
UNII-GN8S7ZES0F
Metaniazida [INN-Spanish]
Methaniazidum [INN-Latin]
EINECS 236-605-3
METHANIAZIDE [MART.]
METHANIAZIDE [WHO-DD]
SCHEMBL606355
CHEMBL2105190
DTXSID2048248
CHEBI:134943
GQZQCROBCYNTMU-UHFFFAOYSA-N
ISONIAZID METHANESULFONATE [MI]
ISONIAZIDE SODIUM METHANESULFONATE
NS00024344
D08198
[(pyridin-4-yl)formohydrazido]methanesulfonic acid
Q27279190
4-PYRIDINECARBOXYLIC ACID 2-(SULFOMETHYL)HYDRAZIDE