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2-(pyridine-4-carbonylhydrazono)propanoic acid

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Identification
Molecular formula
C9H9N3O3
CAS number
85163-40-4
IUPAC name
2-(pyridine-4-carbonylhydrazono)propanoic acid
State
State

At room temperature, 2-(pyridine-4-carbonylhydrazono)propanoic acid is typically present in solid form. Its structure provides stability as a dry, crystalline powder which is crucial for its roles in chemical syntheses and applications.

Melting point (Celsius)
118.00
Melting point (Kelvin)
391.15
Boiling point (Celsius)
261.00
Boiling point (Kelvin)
534.15
General information
Molecular weight
207.21g/mol
Molar mass
207.2050g/mol
Density
1.3206g/cm3
Appearence

2-(Pyridine-4-carbonylhydrazono)propanoic acid typically appears as a yellowish solid. It is a specialized compound often used in chemical synthesis and research, but visual inspection can reveal distinct crystal formations for purity assessment.

Comment on solubility

Solubility of 2-(pyridine-4-carbonylhydrazono)propanoic acid

The solubility of 2-(pyridine-4-carbonylhydrazono)propanoic acid is a topic of interest due to its unique chemical structure, which influences its interactions with various solvents.

In general, the solubility characteristics can be summarized as follows:

  • Polar Solvents: This compound tends to show better solubility in polar solvents such as water or methanol due to its hydrophilic functional groups.
  • Nonpolar Solvents: Conversely, 2-(pyridine-4-carbonylhydrazono)propanoic acid is likely to be less soluble in nonpolar solvents like hexane or toluene, as the lack of polar interactions leads to reduced solubility.

Factors affecting solubility include:

  • The presence of functional groups that can form hydrogen bonds.
  • The molecular size and overall polarity of the compound.
  • Temperature, where increased temperatures may enhance solubility in many cases.

In conclusion, understanding the solubility of 2-(pyridine-4-carbonylhydrazono)propanoic acid is crucial for its practical applications, which require careful manipulation of solvent environments for optimal use. It’s important to note that “like dissolves like” serves as a guiding principle in predicting solubility behavior.

Interesting facts

Interesting Facts about 2-(pyridine-4-carbonylhydrazono)propanoic acid

2-(pyridine-4-carbonylhydrazono)propanoic acid is a fascinating compound that combines elements of both organic chemistry and medicinal chemistry. Here are some compelling aspects of this compound:

  • Structural Diversity: The compound features a hydrazone linkage, which is known for its ability to form through the condensation reaction between an aldehyde and a hydrazine. This structural component is pivotal in many biological activities.
  • Biological Relevance: Compounds with hydrazone functional groups are often studied for their potential therapeutic applications. They have garnered attention for their role in pharmaceutical drugs and their capacity to act as antimicrobial and anticancer agents.
  • Research Applications: This compound can serve as a useful scaffold for designing new derivatives, which may exhibit enhanced biological properties. Chemists are particularly intrigued by how modifications to the pyridine ring can influence reactivity and selectivity in biological systems.
  • Synthetic Pathways: The synthesis of 2-(pyridine-4-carbonylhydrazono)propanoic acid often involves strategic reactions that allow chemists to introduce specific functional groups. This provides insight into the methods of constructing complex molecules.
  • Intermolecular Interactions: Research into this compound can reveal how it interacts at a molecular level, including hydrogen bonding and dipole-dipole interactions, which are crucial for understanding its activity and stability.

In summary, 2-(pyridine-4-carbonylhydrazono)propanoic acid stands out not just for its unique structure, but also for the wealth of opportunities it offers in the exploration of medicinal chemistry and synthetic methods. As noted in the scientific community, “The key to new discoveries often lies in the intricate details of compound structures.” This reminds us of the infinite possibilities in the realm of chemical research!

Synonyms
Isoniazid pyruvate
UNII-5J3GMG27SA
Isonicotinoylhydrazonopyruvic acid
NSC 97221
BRN 0185611
5J3GMG27SA
4-Pyridinecarboxylic acid, (1-carboxyethylidene)hydrazide
L 1011
1081-50-1
5-22-02-00252 (Beilstein Handbook Reference)
ISONICOTINIC ACID, (1-CARBOXYETHYLIDENE)HYDRAZIDE
DTXCID2031407
NSC-97221
ISONICOTINYL HYDRAZONE PYRUVATE
PYRUVIC ACID ISONICOTINOYLHYDRAZONE
4-Pyridinecarboxylic acid, (1-carboxyethylidene)hydrazide (9CI)
4-PYRIDINECARBOXYLIC ACID, 2-(1-CARBOXYETHYLIDENE)HYDRAZIDE
dtxsid1057618
2-(pyridine-4-carbonylhydrazinylidene)propanoic acid
pyruvic acid isonicotinoyl hydrazone