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2-pyridylmethyl acetate

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Identification
Molecular formula
C8H9NO2
CAS number
18953-21-0
IUPAC name
2-pyridylmethyl acetate
State
State

The compound is a liquid at room temperature.

Melting point (Celsius)
-12.00
Melting point (Kelvin)
261.15
Boiling point (Celsius)
243.00
Boiling point (Kelvin)
516.15
General information
Molecular weight
151.18g/mol
Molar mass
151.1770g/mol
Density
1.1451g/cm3
Appearence

2-Pyridylmethyl acetate is a colorless liquid in its pure form. It may appear slightly yellow if impurities are present.

Comment on solubility

Solubility of 2-pyridylmethyl acetate

2-pyridylmethyl acetate, with the chemical formula C10H11NO2, presents interesting solubility characteristics worth noting:

  • Polar Nature: Due to the presence of the polar acetate group, 2-pyridylmethyl acetate is generally soluble in polar solvents such as water and alcohols.
  • Hydrophobic Character: The aromatic pyridine component contributes to its hydrophobic nature, making it less soluble in non-polar solvents.
  • Solvent Selection: Optimal solvents for dissolving this compound include ethanol and dimethyl sulfoxide (DMSO), where it exhibits good miscibility.

As a general rule, it can be said that:

  1. “Like dissolves like” — polar compounds are best soluble in polar solvents.
  2. 2-pyridylmethyl acetate's solubility expands in the presence of functional groups that can form hydrogen bonds.

In summary, 2-pyridylmethyl acetate is moderately soluble in polar solvents, presenting valuable insights for its practical applications in various chemical processes and industries.

Interesting facts

Exploring 2-Pyridylmethyl Acetate

2-Pyridylmethyl acetate is an intriguing compound with potential applications across various fields. As an ester formed from the reaction of acetic acid and 2-pyridylmethanol, it combines features of both the aromatic pyridine ring and a functional acetate group, making it distinctly noteworthy in organic chemistry.

Key Characteristics

  • Versatile Building Block: This compound is often employed in the synthesis of more complex molecules. Its unique structure allows for further functionalization, facilitating a range of reactions that are vital in organic synthesis.
  • Biological Relevance: The pyridine ring in 2-pyridylmethyl acetate is known to exhibit biological activity. Research has shown that pyridine derivatives can interact with biological systems, potentially offering pharmacological benefits.
  • Flavor and Fragrance Industry: Esters like 2-pyridylmethyl acetate are also valued for their pleasant aromas, contributing to flavoring and fragrance formulations.

Interesting Applications

Recent studies have highlighted several fascinating applications of 2-pyridylmethyl acetate:

  1. As a reagent in organic reactions: It can act as a nucleophile or electrophile, opening doors to various synthetic pathways.
  2. In the development of agrochemicals: Its derivatives are being explored for use in pesticides and herbicides.
  3. Potential pharmaceuticals: Due to its biological activity, research is ongoing to evaluate its role in drug development.

As with many compounds in organic chemistry, understanding 2-pyridylmethyl acetate is pivotal for those aiming to innovate in both academic and industrial settings. Its unique characteristics and versatility underscore the importance of esters in diverse chemical applications.

Synonyms
2-Pyridylmethyl acetate
1007-49-4
pyridin-2-ylmethyl acetate
2-Pyridinemethanol, 2-acetate
Pyridine, 2-acetoxymethyl-
2-Acetoxymethylpyridine
2-Pyridylcarbinol acetate (ester)
Acetic acid, 2-pyridylmethyl ester
2-PYRIDINEMETHANOL, ACETATE (ester)
2-(Acetoxymethyl)pyridine
NSC 33131
NSC 44086
MFCD00023518
WLN: T6NJ B1OV1
Pyridine-2-methyl acetate
2-Picolyl acetate
EINECS 213-756-3
BRN 0122621
picolinyl acetate
pyridin-2-ylmethylacetate
2-Pyridylcarbinol acetate
2-pyridinemethanol acetate
2-(acetoxymethyl) pyridine
2-(acetoxymethyl)-pyridine
2-Pyridinemethanol, acetate
2-Pyridinylmethyl acetate #
(pyridin-2-yl)methyl acetate
SCHEMBL533732
PYRIDINE,2-ACETOXYMETHYL
2-[(acetyloxy)-methyl]pyridine
DTXSID80143464
NSC33131
NSC44086
NSC-33131
NSC-44086
AKOS005067814
BS-52013
SY287916
CS-0187774
NS00022998
2-(2-(hydroxymethyl)-2lambda5-pyridin-2-yl)acetate
Q63409263