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Orphenadrine hydrochloride

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Identification
Molecular formula
C18H24ClNO2
CAS number
5987-82-6
IUPAC name
2-pyrrolidin-1-ium-1-ylpropyl 2,6-dimethyl-4-propoxy-benzoate;chloride
State
State
The compound is typically found as a solid at room temperature. In its pharmaceutical form, it is presented as a tablet.
Melting point (Celsius)
143.00
Melting point (Kelvin)
416.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
313.86g/mol
Molar mass
313.8630g/mol
Density
1.0676g/cm3
Appearence

Orphenadrine hydrochloride typically appears as a white or off-white crystalline powder. This appearance is typical for many pharmaceutical compounds in its category.

Comment on solubility

Solubility of 2-pyrrolidin-1-ium-1-ylpropyl 2,6-dimethyl-4-propoxy-benzoate; chloride

The solubility of 2-pyrrolidin-1-ium-1-ylpropyl 2,6-dimethyl-4-propoxy-benzoate; chloride can be influenced by various factors. Understanding its solubility characteristics is crucial for applications in pharmaceuticals and material science. Here are some key points to consider:

  • Polar and Non-Polar Interactions: This compound contains both polar and non-polar functional groups, which suggests that it may exhibit amphipathic behavior.
  • Water Solubility: Given the presence of the pyrrolidinium group, the compound is likely to be soluble in water due to its ionic nature, especially when considering the chloride counterion.
  • Organic Solvents: The non-polar propoxy group may enhance solubility in organic solvents, promoting miscibility with a variety of organic compounds.
  • Temperature Effects: Solubility might increase with temperature, common for many ionic compounds, therefore temperature adjustments might be necessary for optimal solvation.
  • pH Influence: Changes in pH could also affect solubility, especially for ionic species—pyrrolidinium ions may become protonated or deprotonated based on the surrounding environment.

In summary, the solubility of this compound is likely to vary significantly between different solvents, making it essential to ascertain the specific conditions for desired applications. Understanding these solubility aspects will support better handling and utilization of the compound in various fields.

Interesting facts

Interesting Facts about 2-Pyrrolidin-1-ium-1-ylpropyl 2,6-dimethyl-4-propoxy-benzoate; chloride

This compound, known for its complex structure and unique properties, falls under the category of quaternary ammonium salts. These are fascinating due to their versatile applications in various fields, including pharmaceuticals, agriculture, and materials science.

Applications

  • Pharmaceuticals: This compound may function as a potential drug candidate, contributing to the development of novel therapeutic agents.
  • Surfactants: Quaternary ammonium compounds are often used as surfactants, which help to lower the surface tension between two substances, making them useful in detergents and emulsifiers.
  • Antimicrobial Activity: Many compounds of this class exhibit antimicrobial properties, making them important in disinfectants and preservatives.

Structure-Activity Relationship

The specific arrangement of atoms and functional groups in 2-pyrrolidin-1-ium-1-ylpropyl 2,6-dimethyl-4-propoxy-benzoate plays a crucial role in determining its biological activity and interaction with other molecules. The pyrrolidine ring provides a flexible structure that can engage in hydrogen bonding, potentially enhancing the compound's solubility and bioavailability.

Research Insights

Recent studies have focused on understanding the mechanism of action of similar compounds, exploring how structural variations influence their reactivity and interactions with biological targets. As researchers dive deeper, they reveal the intricate connections between chemical structure and function.

In conclusion, 2-pyrrolidin-1-ium-1-ylpropyl 2,6-dimethyl-4-propoxy-benzoate; chloride represents not just a chemical entity, but a gateway to advancements in multiple scientific domains. Its unique attributes are a reminder of the elegance and complexity inherent in the world of chemistry.

Synonyms
2,6-Dimethyl-4-propoxy-benzoic acid 2-(1-pyrrolidinyl)propyl ester hydrochloride
3737-66-4
U 2397
Benzoic acid, 2,6-dimethyl-4-propoxy-, 2-(1-pyrrolidinyl)propyl ester, hydrochloride