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2-(quinoxaline-2-carbonylamino)acetic acid

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Identification
Molecular formula
C12H9N3O3
CAS number
19386-44-2
IUPAC name
2-(quinoxaline-2-carbonylamino)acetic acid
State
State

At room temperature, 2-(quinoxaline-2-carbonylamino)acetic acid is typically found in a solid state. It is stable under normal conditions and dissolves in organic solvents like dimethyl sulfoxide and methanol.

Melting point (Celsius)
261.00
Melting point (Kelvin)
534.15
Boiling point (Celsius)
405.00
Boiling point (Kelvin)
678.15
General information
Molecular weight
259.25g/mol
Molar mass
259.2530g/mol
Density
1.3670g/cm3
Appearence

2-(quinoxaline-2-carbonylamino)acetic acid typically appears as a white or off-white crystalline powder. Its crystalline form is due to the structure of the molecule, which is often tightly packed. This compound may be sensitive to air and light, resulting in slight discoloration over time.

Comment on solubility

Solubility of 2-(quinoxaline-2-carbonylamino)acetic acid

The solubility of 2-(quinoxaline-2-carbonylamino)acetic acid is influenced by several key factors, including its molecular structure and functional groups. Understanding its solubility characteristics can help in various applications, especially in pharmaceuticals and biochemistry.

Factors Affecting Solubility

  • Polarity: The presence of polar functional groups, such as the carboxylic acid and amine groups, contributes to the compound's ability to interact with water molecules, potentially improving its solubility.
  • Hydrogen Bonding: The capability of 2-(quinoxaline-2-carbonylamino)acetic acid to form hydrogen bonds can enhance its solubility in polar solvents.
  • pH Influence: The solubility may vary with pH; in acidic solutions, it may exist predominantly as a neutral species, while in basic conditions, it may ionize and increase solubility.

In general, compounds with a balance of hydrophobic and hydrophilic character tend to exhibit moderate solubility. For this compound, the presence of both carbonyl and amino groups suggests that it may have reasonable solubility in polar solvents such as water, but this would need to be verified through experimental data.

In conclusion, 2-(quinoxaline-2-carbonylamino)acetic acid exhibits potential for solubility in aqueous environments, largely due to its polar functionalities and ability to engage in hydrogen bonding. Further studies would illuminate its precise solubility profile and better inform its applications.

Interesting facts

Interesting Facts about 2-(quinoxaline-2-carbonylamino)acetic acid

2-(quinoxaline-2-carbonylamino)acetic acid is a fascinating compound that lies at the intersection of organic chemistry and pharmaceutical research. Here are some intriguing details about this unique molecule:

  • Quinoxaline Moiety: The compound features a quinoxaline ring, which is a bicyclic structure known for its biological activity. Compounds containing quinoxaline have been studied for their potential as antibacterial and antitumor agents.
  • Amidation Characteristics: The presence of the carbonylamino functional group makes 2-(quinoxaline-2-carbonylamino)acetic acid a useful intermediate in the synthesis of other more complex organic compounds. This properties enhance its reactivity towards various chemical transformations.
  • Role in Drug Development: Researchers are continually interested in derivatives of this compound due to their potential therapeutic applications. Investigations have indicated that modifications could lead to new drugs targeting a variety of diseases.
  • Biological Studies: In biochemical research, 2-(quinoxaline-2-carbonylamino)acetic acid serves as a valuable tool in studying enzyme interactions and pathways. Its unique structure can help in the design of inhibitors that selectively interact with specific biological targets.

Overall, compounds like 2-(quinoxaline-2-carbonylamino)acetic acid illustrate the importance of understanding molecular structure and its implications in developing new therapeutic agents. As noted by researchers, "the intricacies of organic compounds open doors to countless applications in medicine and technology." With ongoing studies, the potential of this compound may just be the tip of the iceberg in the field of medicinal chemistry.

Synonyms
5569-99-3
GLYCINE, N-(2-QUINOXALOYL)-
N-(2-Quinoxaloyl)-glycine
Glycine, N-(2-quinoxalinylcarbonyl)-
2-(Quinoxaline-2-carboxamido)acetic acid
2-(quinoxaline-2-carbonylamino)acetic acid
2-[(quinoxalin-2-yl)formamido]acetic acid
NSC 70625
BRN 0533185
WLN: T66 BN ENJ CVM1VQ
NSC70625
Glycine, N-(2-quinoxalinylcarbonyl)- (9CI)
5-25-04-00347 (Beilstein Handbook Reference)
DTXSID80204221
NSC-70625
AKOS005068104
[(2-quinoxalinylcarbonyl)amino]acetic acid
AE-641/40198076