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2-Mercaptobenzimidazole-4-carboxylic acid

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Identification
Molecular formula
C8H6N2O2S
CAS number
43229-65-8
IUPAC name
2-sulfanyl-1H-benzimidazole-4-carboxylic acid
State
State

At room temperature, this compound is typically found in a solid state. It is stable under normal conditions and shows no tendency to evaporate.

Melting point (Celsius)
275.00
Melting point (Kelvin)
548.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
194.22g/mol
Molar mass
194.2230g/mol
Density
1.7263g/cm3
Appearence

2-Mercaptobenzimidazole-4-carboxylic acid is a white or off-white crystalline powder. It is typically odorless and is characterized by its solid form at room temperature.

Comment on solubility

Solubility of 2-sulfanyl-1H-benzimidazole-4-carboxylic acid

The solubility of 2-sulfanyl-1H-benzimidazole-4-carboxylic acid is a significant aspect to consider, particularly given its potential applications in various fields. Here are some key points regarding its solubility:

  • Solvent Interaction: This compound shows varying solubility in different solvents. It tends to be more soluble in polar solvents such as water and ethanol.
  • pH Dependency: The solubility can be affected by the pH of the solution due to the presence of the carboxylic acid group, which can dissociate, increasing solubility in more alkaline environments.
  • Temperature Influence: Like many organic compounds, an increase in temperature generally enhances solubility, allowing for better dissolution of the compound.
  • Crystallization Behavior: The compound may exhibit a tendency to crystallize, which can affect its apparent solubility, especially when conditions favor supersaturation.

In conclusion, while 2-sulfanyl-1H-benzimidazole-4-carboxylic acid demonstrates moderate solubility in various environments, understanding the specific conditions such as solvent type, pH, and temperature is essential for optimizing its use in practical applications. As noted, “the devil is in the details” when it comes to solubility behavior.

Interesting facts

Interesting Facts about 2-sulfanyl-1H-benzimidazole-4-carboxylic acid

2-sulfanyl-1H-benzimidazole-4-carboxylic acid, often abbreviated as SBA, is a fascinating compound that plays a significant role in various fields of research, particularly in medicinal chemistry and drug development. Here are some intriguing facts about this compound:

  • Structural Significance: This compound features a unique structure that integrates both a benzimidazole moiety and a carboxylic acid group, which contributes to its diverse biological activities.
  • Biological Activity: Studies have shown that derivatives of 2-sulfanyl-1H-benzimidazole can exhibit potent antimicrobial and antifungal properties, making them potentially valuable in the development of new pharmaceuticals.
  • Pharmaceutical Applications: Research indicates that this compound may be used as a scaffold for the development of inhibitors for various enzymes involved in disease pathways, particularly in cancer treatment.
  • Antioxidant Potential: The presence of the sulfanyl group in its structure suggests possible antioxidant properties, a feature that could be exploited in the treatment of oxidative stress-related diseases.
  • Versatile Synthesis: 2-sulfanyl-1H-benzimidazole-4-carboxylic acid can be synthesized through several synthetic routes, which allows for significant modifications to enhance its activity and efficacy.
  • Research Interest: With continuous advances in organic chemistry, compounds like SBA are gaining attention for their potential use in developing targeted therapies in personalized medicine.

In conclusion, 2-sulfanyl-1H-benzimidazole-4-carboxylic acid not only offers intriguing structural features but also paves the way for innovative drug design and discovery. As research advances, this compound might surface as a crucial player in the pharmaceutical industry.