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2-Mercapto-3-pyridinol

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Identification
Molecular formula
C5H5NOS
CAS number
3426-11-5
IUPAC name
2-sulfanylpyridin-3-ol
State
State

At room temperature, 2-Mercapto-3-pyridinol is a solid.

Melting point (Celsius)
119.00
Melting point (Kelvin)
392.15
Boiling point (Celsius)
241.00
Boiling point (Kelvin)
514.15
General information
Molecular weight
127.16g/mol
Molar mass
127.1640g/mol
Density
1.3740g/cm3
Appearence

2-Mercapto-3-pyridinol is a light yellow crystalline solid. It tends to appear as a fine crystalline powder and may have a slight sulfurous odor due to the presence of the mercapto group.

Comment on solubility

Solubility of 2-sulfanylpyridin-3-ol

When discussing the solubility of 2-sulfanylpyridin-3-ol, it is important to consider various factors that influence its behavior in different solvents. Here are some key points to note:

  • Solvent Polarity: 2-sulfanylpyridin-3-ol is expected to exhibit better solubility in polar solvents such as water or ethanol due to its hydroxyl group (-OH) that can engage in hydrogen bonding.
  • Functional Groups: The presence of a thiol group (-SH) enhances its solubility in polar environments, allowing for interactions that stabilize its dissolution.
  • Structural Characteristics: The aromatic nature of the pyridine ring may impart some degree of hydrophobic character, which can influence solubility in non-polar solvents, likely making it less soluble in such scenarios.

As a general observation, compounds that possess both hydrophilic (water-attracting) and hydrophobic (water-repelling) properties often present a unique solubility profile. Hence, understanding the balance between these properties is essential in predicting how 2-sulfanylpyridin-3-ol will behave in various solvent environments.

Ultimately, while empirical data from solubility studies would provide a clearer picture, the theoretical insights suggest a tendency towards moderate solubility in polar solvents, characteristic of similar compounds.

Interesting facts

Interesting Facts about 2-sulfanylpyridin-3-ol

2-sulfanylpyridin-3-ol is a fascinating compound with a variety of properties and uses in both organic chemistry and medicinal applications. Here are some intriguing facts about this compound:

  • Structural Features: This compound features a pyridine ring, which is known for its aromatic properties, along with a thiol (-SH) group that imparts significant reactivity.
  • Chemical Behavior: Due to its thiol group, 2-sulfanylpyridin-3-ol can engage in unique reactions, including oxidation and conjugation. It’s often utilized in synthesizing other complex organic molecules.
  • Biological Relevance: Compounds with thiol functions are important in biological systems. They can act as antioxidants, potentially playing a role in mitigating oxidative stress within cells.
  • Pharmacological Potential: Research indicates that analogous compounds may exhibit antimicrobial and anti-inflammatory properties, making this class of compounds of interest in drug development.
  • Role in Synthesis: The ability to participate in various chemical reactions makes 2-sulfanylpyridin-3-ol a valuable intermediate in the creation of pharmaceutical compounds and agrochemicals.

As a student or scientist, you may find it particularly interesting to investigate the potential applications of 2-sulfanylpyridin-3-ol in various fields such as environmental science, medicine, and agriculture. The versatility of the thiol group makes it a target for numerous synthetic strategies, which can lead to the development of novel compounds.

In summary, while 2-sulfanylpyridin-3-ol may seem modest at first glance, its unique chemical properties and potential applications make it a noteworthy subject of study in the realm of chemistry.