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Bupropion

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Identification
Molecular formula
C13H18ClNO
CAS number
34841-39-9
IUPAC name
2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol
State
State

Bupropion is generally found as a solid at room temperature.

Melting point (Celsius)
234.15
Melting point (Kelvin)
507.30
Boiling point (Celsius)
374.15
Boiling point (Kelvin)
647.30
General information
Molecular weight
239.33g/mol
Molar mass
239.3280g/mol
Density
1.1525g/cm3
Appearence

Bupropion is typically encountered as a white, crystalline powder. It is often formulated into tablets for pharmaceutical use.

Comment on solubility

Solubility of 2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol

The solubility of 2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol can be described as follows:

  • Polar Nature: Due to the presence of both hydrophilic (amino group) and hydrophobic (tert-butyl and aromatic groups) segments in the molecule, this compound exhibits a balance of polarity.
  • Solubility in Water: It is moderately soluble in water, primarily influenced by the basicity of the amino group which can interact favorably with water molecules.
  • Organic Solvents: The molecule is expected to be more soluble in organic solvents such as ethanol, methanol, and chloroform. This is attributed to its hydrophobic parts which can engage in favorable interactions with non-polar solvent environments.
  • Concentration Dependence: Its solubility may also vary with concentration; hence, performing solubility tests at different concentrations can yield more specific information.

Understanding the solubility of this compound is crucial for its applications in various chemical processes and formulations. As a rule of thumb, "like dissolves like" – polar solvents will favorably dissolve polar compounds and vice versa.

Interesting facts

About 2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol

2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol is a fascinating compound that intersects the fields of organic chemistry and pharmacology. Here are some interesting facts about this compound that highlight its significance:

  • Structure and Function: This compound features a unique combination of a tert-butylamino group and a dimethoxy-substituted phenyl ring, creating a versatile structure that may alter biological activity compared to similar compounds.
  • Potential Applications: Due to its structural components, 2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol is of interest in medicinal chemistry, particularly in the development of novel therapeutic agents that can modulate neurotransmitter systems.
  • Exploration in Research: Scientists are currently investigating how derivatives of this compound can influence both central nervous system (CNS) activity and other physiological pathways.
  • Inhibition and Activation: Compounds like this can serve as inhibitors or activators in various biological pathways, making them valuable tools in the study of complex biological systems.
  • Chemical Synthesis: The synthesis of this compound entails strategic manipulation of functional groups, requiring familiarity with techniques such as amine protection and selective methylation.

In conclusion, 2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol is not just a name; it represents a piece of a larger puzzle in understanding complex interactions within biological systems. As researchers continue to explore its potential applications, this compound may well pave the way for innovative treatments and insights in chemical and pharmaceutical sciences.

Synonyms
Butaxamine
Butoxamin
2922-20-5
BUTOXAMINE
2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol
(+/-)-Butoxamine
CHEMBL289093
(+/-)-Butaxamine
d-Butoxamine
GTPL9809
SCHEMBL4745452
DTXSID30897107
DTXSID70896997
BDBM50017713
AKOS022573778
DA-71821
HY-119868
CS-0078193
NS00004491
BRD-A92412021-003-01-2
2-tert-Butylamino-1-(2,5-dimethoxy-phenyl)-propan-1-ol
2-tert-Butylamino-1-(2,5-dimethoxy-phenyl)-propan-1-ol(Butoxamine)
alpha-[1-[(1,1-Dimethylethyl)amino]ethyl]-2,5-dimethoxybenzenemethanol
33997-55-6