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Butaxamine

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Identification
Molecular formula
C12H18FNO
CAS number
17945-22-5
IUPAC name
2-(tert-butylamino)-1-(3-fluorophenyl)ethanol
State
State

At room temperature, it is a solid and is typically stable under standard conditions. It is soluble in organic solvents.

Melting point (Celsius)
115.00
Melting point (Kelvin)
388.20
Boiling point (Celsius)
277.60
Boiling point (Kelvin)
550.80
General information
Molecular weight
211.28g/mol
Molar mass
211.2760g/mol
Density
1.1095g/cm3
Appearence

2-(tert-butylamino)-1-(3-fluorophenyl)ethanol appears as a white crystalline solid. This compound is often used in the form of a hydrochloride salt for laboratory and synthetic purposes.

Comment on solubility

Solubility of 2-(tert-butylamino)-1-(3-fluorophenyl)ethanol

The solubility of 2-(tert-butylamino)-1-(3-fluorophenyl)ethanol can be assessed based on several important factors. This compound, characterized by its unique structure, typically exhibits a solubility profile influenced by:

  • Polarity: The presence of both an amino group and an alcohol group increases polarity, enhancing solubility in polar solvents.
  • Hydrogen Bonding: The -NH and -OH groups facilitate hydrogen bonding, which can significantly improve solubility in water.
  • Substituent Effects: The 3-fluorophenyl group introduces additional interactions that can vary solubility based on the nature of the solvent.

In general, this compound is expected to be more soluble in:

  • Water due to its polar functional groups,
  • Alcohols such as ethanol, which can stabilize its structure through hydrogen bonding,
  • Organic solvents that can accommodate the bulky tert-butyl group while still being polar enough.

However, its solubility in nonpolar solvents will likely be limited due to the overall polar character of the molecule. As with many organic compounds, one should consider specific concentration and temperature conditions for precise solubility data.

In conclusion, understanding the solubility of 2-(tert-butylamino)-1-(3-fluorophenyl)ethanol is crucial for its applications, especially in pharmaceuticals and biochemical processes, where solubility can influence bioavailability and interaction with biological systems.

Interesting facts

Interesting Facts about 2-(tert-butylamino)-1-(3-fluorophenyl)ethanol

2-(tert-butylamino)-1-(3-fluorophenyl)ethanol, a fascinating compound, plays a significant role in medicinal chemistry and pharmacology. Here are some engaging insights that highlight its importance:

  • Pharmacological Potential: This compound has garnered attention for its potential use as a pharmaceutical agent. Its structural features suggest it may interact with specific receptors in the body, making it a candidate for research in therapeutic applications.
  • Structure-Activity Relationship (SAR): The presence of both a tert-butylamino group and a 3-fluorophenyl moiety allows scientists to study how modifications in chemical structure can affect biological activity. Understanding these relationships is crucial for developing effective drugs.
  • Synthesis Challenges: The synthesis of this compound presents interesting challenges that can engage students and researchers alike. Exploring different synthetic routes can lead to a better understanding of organic synthesis techniques and strategies.
  • Fluorine's Influence: The inclusion of a fluorine atom in the phenyl ring can significantly alter the compound's physical and chemical properties. Fluorine substitution is often used to enhance metabolic stability and increase binding affinity to biological targets.
  • Research Applications: The compound is not just of theoretical interest; it serves as a valuable tool in research. Its derivatives and analogs are frequently investigated for their effects on neurotransmitter systems, which can yield insights into various neurological conditions.

Overall, 2-(tert-butylamino)-1-(3-fluorophenyl)ethanol exemplifies how a single compound can bridge the gap between chemistry, biology, and medicine. Its unique features not only showcase the intricacies of organic molecules but also inspire ongoing research in the quest for novel therapeutic agents.

Synonyms
SCHEMBL10537192