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Norephedrine

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Identification
Molecular formula
C14H21NO
CAS number
41939-34-4
IUPAC name
2-(tert-butylamino)-1-(4-cyclopropylphenyl)ethanol
State
State

At room temperature, norephedrine is a solid. Due to its crystalline nature, it is easy to handle and use in various applications, including pharmaceuticals.

Melting point (Celsius)
149.00
Melting point (Kelvin)
422.15
Boiling point (Celsius)
330.50
Boiling point (Kelvin)
603.65
General information
Molecular weight
237.36g/mol
Molar mass
237.3570g/mol
Density
1.0097g/cm3
Appearence

Norephedrine typically appears as a white to off-white crystalline powder. It is often used in the form of its hydrochloride salt, which is water-soluble. This compound is known for its use in medicinal formulations, particularly related to its stimulant and decongestant properties.

Comment on solubility

Solubility of 2-(tert-butylamino)-1-(4-cyclopropylphenyl)ethanol

The solubility of 2-(tert-butylamino)-1-(4-cyclopropylphenyl)ethanol can be influenced by several factors, including its molecular structure, polarity, and the solvent used for dissolution. Generally, this compound exhibits the following characteristics:

  • Polarity: Due to the presence of an amino group and a hydroxyl group, 2-(tert-butylamino)-1-(4-cyclopropylphenyl)ethanol is relatively polar, which significantly affects its solubility in various solvents.
  • Solvent Compatibility: It tends to be soluble in polar protic solvents like water and alcohols. However, it may have limited solubility in nonpolar solvents like hexane or toluene.
  • Temperature Effects: Increasing the temperature generally enhances solubility for most compounds. Thus, warmer conditions may increase the solubility of this compound in appropriate solvents.

In summary, while 2-(tert-butylamino)-1-(4-cyclopropylphenyl)ethanol is likely to show better solubility in polar solvents, understanding the complete solubility profile would require quantitative experimental data or further computational analysis. As a guiding principle, **"like dissolves like"** serves as a useful reminder when predicting solubility behaviors based on molecular interactions.

Interesting facts

Exploring 2-(tert-butylamino)-1-(4-cyclopropylphenyl)ethanol

2-(tert-butylamino)-1-(4-cyclopropylphenyl)ethanol, often referred to in the scientific community as a novel compound, holds significant interest due to its unique structure and potential applications. Here are some fascinating facts about this compound:

  • Pharmaceutical Relevance: This compound is often examined for its potential role in drug development, particularly in the realm of therapeutic agents targeting neurological disorders.
  • Design and Synthesis: The synthesis process involves intricate organic chemistry techniques emphasizing the manipulation of amine functional groups and the cyclopropyl ring, making it a popular subject in synthetic organic chemistry workshops.
  • Structure-Activity Relationships: Researchers study how modifications to the tert-butylamino and cyclopropylphenyl groups can affect the compound's biological activity, leading to discoveries of more efficient drug candidates.
  • Research Applications: It serves as a model compound in studies relating to receptor binding and enzyme inhibition, enhancing our understanding of molecular interactions in biological systems.
  • Interdisciplinary Interest: The compound's unique properties attract attention from various fields, including medicinal chemistry, pharmacology, and materials science, opening avenues for cross-disciplinary research.

In summary, 2-(tert-butylamino)-1-(4-cyclopropylphenyl)ethanol is not just another compound; it embodies numerous concepts and challenges in modern chemistry, making it a rich topic for discussion and investigation within scientific communities. As we delve deeper into its properties and functionalities, the potential for developing innovative solutions appears promising.

Synonyms
AKOS018536860