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Methylene Blue

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Identification
Molecular formula
C16H18N3SCl
CAS number
61-73-4
IUPAC name
2-(tert-butylamino)-1-phenothiazin-10-yl-ethanone
State
State

At room temperature, methylene blue is typically in a solid state, either in the form of a powder or crystals.

Melting point (Celsius)
100.00
Melting point (Kelvin)
373.15
Boiling point (Celsius)
597.00
Boiling point (Kelvin)
870.15
General information
Molecular weight
319.85g/mol
Molar mass
319.8520g/mol
Density
1.2700g/cm3
Appearence

Methylene blue appears as a dark green crystalline powder when anhydrous. In hydrated form, it presents as small, glossy, dark green crystals that produce a blue solution when dissolved in water.

Comment on solubility

Solubility of 2-(tert-butylamino)-1-phenothiazin-10-yl-ethanone

The solubility of 2-(tert-butylamino)-1-phenothiazin-10-yl-ethanone can be characterized by several key factors:

  • Polarity: The presence of polar functional groups, such as the amino group, can influence solubility in polar solvents like water.
  • Solvent Type: The compound is expected to be more soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) than in water, due to its larger nonpolar aromatic component.
  • Hydrogen Bonding: The ability to form hydrogen bonds may increase solubility in polar solvents, making interactions with molecules like water more favorable.
  • Temperature Influence: As with many organic compounds, solubility can improve with an increase in temperature, enhancing the kinetic energy and interactions among molecules.

In summary, while 2-(tert-butylamino)-1-phenothiazin-10-yl-ethanone's solubility profile may vary, it is anticipated to show better solubility in polar organic solvents due to its molecular structure. As always, it should be acknowledged that experimental verification is essential for precise solubility measurements.

Interesting facts

Interesting Facts about 2-(tert-butylamino)-1-phenothiazin-10-yl-ethanone

This compound, known for its unique structure and biological properties, is a derivative of phenothiazine, a classic scaffold in medicinal chemistry. Here are some fascinating aspects:

  • Medicinal Relevance: The phenothiazine backbone is commonly found in several antipsychotic medications, showcasing the importance of this compound in pharmaceutical research.
  • Structural Features: The presence of a tert-butylamino group influences the compound's lipophilicity, potentially affecting its interaction with biological membranes and targets.
  • Diverse Applications: Beyond its medicinal uses, phenothiazines and their derivatives are also explored for their applications in photodynamic therapy, highlighting the compound's versatility and potential for innovation.
  • Research Interest: Ongoing studies may reveal new insights into its mechanism of action, contributing to advanced therapies in the treatment of various mental health disorders.

In conclusion, 2-(tert-butylamino)-1-phenothiazin-10-yl-ethanone exemplifies the intricate relationship between chemical structure and biological function, making it a subject of great interest in both academic research and pharmaceutical development.