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Menadione

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Identification
Molecular formula
C11H8O2
CAS number
58-27-5
IUPAC name
2-(tert-butylamino)naphthalene-1,4-dione
State
State

At room temperature, menadione is in a solid state. It is typically handled as a powder.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.15
Boiling point (Celsius)
486.00
Boiling point (Kelvin)
759.15
General information
Molecular weight
172.18g/mol
Molar mass
172.1800g/mol
Density
1.2560g/cm3
Appearence

Menadione appears as a bright yellow crystalline solid. It is usually found in powder form and is known for its vivid yellow color.

Comment on solubility

Solubility of 2-(tert-butylamino)naphthalene-1,4-dione

The solubility of 2-(tert-butylamino)naphthalene-1,4-dione in various solvents can be quite intriguing due to its unique chemical structure and functional groups. Understanding solubility is essential for practical applications in chemical synthesis and formulation. Here are some points to consider:

  • Polar vs. Non-Polar Solvents: Given that the compound features a naphthalene core with a tert-butylamino group, it exhibits a tendency to dissolve well in non-polar organic solvents due to its hydrophobic characteristics.
  • Water Solubility: This compound is expected to have limited solubility in water. The presence of the bulky tert-butyl group may hinder interactions with water molecules, resulting in low aqueous solubility.
  • Temperature Dependence: The solubility profile is likely to change with temperature. Heating the solvent generally increases solubility for organic compounds.

In conclusion, the solubility of 2-(tert-butylamino)naphthalene-1,4-dione is majorly influenced by its structural characteristics, with a preference for non-polar solvents while showing poor compatibility with water. As always, experimental determination is crucial to fully understand the solubility behavior of this compound in various environments.

Interesting facts

Interesting Facts about 2-(tert-butylamino)naphthalene-1,4-dione

2-(tert-butylamino)naphthalene-1,4-dione, commonly referred to as a naphthoquinone derivative, is an intriguing compound that garners interest in various fields of chemistry, particularly in organic synthesis and medicinal chemistry. Here are some noteworthy aspects of this compound:

  • Structural Significance: The presence of the tert-butylamino group enhances the lipophilicity of the compound, which can influence its biological activity and interaction with lipid membranes.
  • Reactivity: Naphthoquinones are known for their reactivity due to the presence of conjugated double bonds. This makes them valuable in organic syntheses as intermediates in the production of more complex molecules.
  • Biological Activities: Compounds like 2-(tert-butylamino)naphthalene-1,4-dione have been studied for their potential therapeutic properties, including antibacterial and anticancer activities, which could pave the way for new drug developments.
  • Application in Dyes: Similar naphthalene derivatives are frequently utilized in the dye industry due to their vivid colors and stability, showcasing their importance beyond medicinal chemistry.
  • Analytical Uses: Given its unique structure and properties, this compound can be employed as a reagent in analytical chemistry, particularly in qualitative and quantitative analysis of various substrates.

In the words of renowned chemists, “Understanding the structure-activity relationship is crucial for the development of effective pharmaceuticals.”

As the study of compounds like 2-(tert-butylamino)naphthalene-1,4-dione continues, researchers are constantly unveiling new applications and significance, making the exploration of chemical compounds a vibrant and ever-evolving field.

Synonyms
23434-49-3
1,4-NAPHTHOQUINONE, 2-tert-BUTYLAMINO-
SS7XVE07AE
NSC-222689
1,4-Naphthalenedione, 2-((1,1-dimethylethyl)amino)-
DTXSID80177986
2-((1,1-Dimethylethyl)amino)-1,4-naphthalenedione
RefChem:1060442
DTXCID40100477
2-tert-Butylamino-1,4-naphthoquinone
2-t-Butylamino-1,4-naphthoquinone
NSC 222689
BRN 2838090
NSC222689
1, 2-tert-butylamino-
UNII-SS7XVE07AE
1, 2-[(1,1-dimethylethyl)amino]-
1,4-NAPHTHOQUINONE, 2-(TERT-BUTYLAMINO)-