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2-Tetralin-5-ylacetamide

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Identification
Molecular formula
C12H15NO
CAS number
.
IUPAC name
2-tetralin-5-ylacetamide
State
State

At room temperature, 2-Tetralin-5-ylacetamide is in a solid state. It is a stable compound and maintains its form unless subjected to temperatures nearing its melting point.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
189.26g/mol
Molar mass
189.2570g/mol
Density
1.1000g/cm3
Appearence

2-Tetralin-5-ylacetamide is a white crystalline solid. Its crystalline nature gives it a distinct, shiny appearance under light. It is relatively stable under normal conditions.

Comment on solubility

Solubility of 2-tetralin-5-ylacetamide (C12H15NO)

When discussing the solubility of 2-tetralin-5-ylacetamide, we encounter a compound whose solubility is influenced by its chemical structure and functional groups. This compound is known to exhibit the following characteristics concerning its solubility:

  • Solvent Compatibility: 2-tetralin-5-ylacetamide is generally more soluble in organic solvents due to its hydrophobic aromatic rings and the presence of an amide functional group.
  • Polarity: The amide group can engage in hydrogen bonding, enhancing its solubility in polar solvents like alcohols and some ketones.
  • Temperature Dependency: Solubility may increase with temperature, indicating that higher temperatures can lead to better dispersion in solvents.
  • Concentration Limits: It's important to note that saturation levels can vary significantly based on the solvent and environmental conditions.

Thus, while 2-tetralin-5-ylacetamide demonstrates appreciable solubility in several organic solvents, it may pose challenges when attempting to dissolve in purely aqueous systems due to its overall hydrophobic character. As stated, "The solubility profile is a balance between molecular interactions and solvent properties."

Interesting facts

Interesting Facts about 2-tetralin-5-ylacetamide

2-tetralin-5-ylacetamide is a fascinating compound in the realm of organic chemistry, notable for its unique structural features and potential applications. Below are some intriguing points to consider:

  • Structural Composition: This compound features a tetralin moiety, a bicyclic structure that contributes to its interesting chemical behavior. The combination of a carbon skeleton with a nitrogen-containing functional group is an area of active study.
  • Chemical Reactivity: As an amide, 2-tetralin-5-ylacetamide may undergo a variety of reactions typical for amides, such as hydrolysis and exchange reactions, making it a valuable compound for synthetic chemists.
  • Potential Applications: The presence of both an aromatic system and an amide could suggest potential uses in pharmaceuticals or agrochemicals. Compounds like this are often explored for their biological activity and could serve as precursors for more complex molecules.
  • Research Relevance: 2-tetralin-5-ylacetamide—and similar amides—are subjects of interest in research involving drug design and synthetic organic chemistry. They can provide insight into structure-activity relationships (SAR) in medicinal chemistry.
  • Natural Occurrences: Some tetralin derivatives are found in natural products and may play roles in the biosynthesis of secondary metabolites, showcasing the connection between synthetic chemistry and nature.

In conclusion, 2-tetralin-5-ylacetamide represents a unique blend of structural and functional properties that makes it an engaging compound for study. As researchers continue to explore its potential, it reinforces the importance of organic compounds in advancing scientific knowledge.

Synonyms
alpha-Tetralylacetic acid amide
BRN 3263478
1-NAPHTHALENEACETAMIDE, 5,6,7,8-TETRAHYDRO-
13052-98-7
5,6,7,8-Tetrahydro-1-naphthaleneacetamide
DTXSID30156589
DTXCID7079080
4-09-00-02120 (beilstein handbook reference)