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2-triethylsilyloxyethanamine

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Identification
Molecular formula
C8H21NO1Si1
CAS number
34804-56-7
IUPAC name
2-triethylsilyloxyethanamine
State
State

This compound is a liquid at room temperature. It remains stable as a liquid under normal laboratory conditions.

Melting point (Celsius)
-90.00
Melting point (Kelvin)
183.15
Boiling point (Celsius)
187.90
Boiling point (Kelvin)
461.05
General information
Molecular weight
177.35g/mol
Molar mass
177.3760g/mol
Density
0.8260g/cm3
Appearence

2-Triethylsilyloxyethanamine is a colorless liquid compound that is commonly used as a silane protecting group in organic synthesis. The compound is often found in laboratories where it is utilized for various chemical reactions and molecular protection purposes. It is typically stored in standard laboratory containers to prevent any exposure to the ambient environment.

Comment on solubility

Solubility of 2-triethylsilyloxyethanamine

The solubility of 2-triethylsilyloxyethanamine can be discussed in the context of its chemical structure and characteristics. The presence of the triethylsilyloxy group contributes to its unique solubility properties.

Factors Influencing Solubility

  • Polar vs Nonpolar: The balance between the hydrophilic triethylsilyloxy group and the hydrophobic ethylene backbone plays a crucial role in solubility.
  • Solvent Interactions: This compound is likely soluble in organic solvents such as dichloromethane and possibly soluble in alcohols, but may have limited solubility in polar solvents like water.
  • Temperature Effects: Increased temperature may enhance solubility, making it more favorable for use in various chemical reactions where higher temperatures are employed.

Generally, compounds like 2-triethylsilyloxyethanamine exhibit limited to moderate solubility in water while demonstrating better solubility in organic solvents due to their organic nature. As with many silyl compounds, interaction with moisture should also be approached with caution, causing further implications for their behavior in aqueous environments.

Understanding the solubility profile of this compound is vital for applications in synthesis and formulation, ensuring proper handling and maximum effectiveness in chemical processes.

Interesting facts

Interesting Facts about 2-Triethylsilyloxyethanamine

2-Triethylsilyloxyethanamine is a fascinating chemical compound that plays a significant role in organic syntheses and medicinal chemistry. Here are some noteworthy aspects that make this compound stand out:

  • Silicon in Chemistry: The incorporation of a triethylsilyl group in the structure allows for unique reactivity patterns. Silicon is known for its ability to stabilize anions, which enhances the selectivity of chemical reactions involving this compound.
  • Versatility: This compound serves as a versatile building block in organic synthesis, particularly in the preparation of more complex molecules. It can act as a synthetic intermediate in the formation of amines, alcohols, and other functional groups.
  • Applications in Drug Development: 2-Triethylsilyloxyethanamine has potential therapeutic applications. Its functional groups can be modified for enhanced pharmacological properties, making it a valuable substrate in drug discovery and development.
  • Silicon-Carbon Interaction: The compound exhibits interesting properties arising from the silicon-carbon bond, which can alter the physical properties and reactivity compared to traditional carbon-based amines.
  • Protecting Groups: In organic synthesis, the triethylsilyl group is often used as a protecting group for alcohols and amines, allowing chemists to selectively perform reactions without interfering with these functional groups.

As chemists delve deeper into this compound's unique structure and properties, it becomes evident that 2-triethylsilyloxyethanamine is not just a chemical entity but a gateway to understanding broader concepts in silicon chemistry and its applications in various fields.

Synonyms
2-triethylsilyloxyethanamine
18419-91-5
Ethanamine, 2-((triethylsilyl)oxy)-(9CI)
2-Aminoethyl triethylsilyl ether
(2-Aminoethyl)triethylsilane
(2-Aminoethoxy)triethylsilane
BRN 1739686
Silane, (2-aminoethoxy)triethyl-
Ethanamine, 2-((triethylsilyl)oxy)-
ETHYLAMINE, 2-(TRIETHYLSILOXY)-
Ethanamine, 2-((triethylsilyl)oxy)- (9CI)
4-04-00-04050 (Beilstein Handbook Reference)
2-Triethylsilanyloxy-ethylamine
DTXSID40171546