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2-(trifluoromethyl)phenothiazine

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Identification
Molecular formula
C13H8F3NOS
CAS number
1534-76-3
IUPAC name
2-(trifluoromethyl)-10H-phenothiazine
State
State

At room temperature, 2-(trifluoromethyl)-10H-phenothiazine is in a solid state.

Melting point (Celsius)
126.00
Melting point (Kelvin)
399.15
Boiling point (Celsius)
378.20
Boiling point (Kelvin)
651.35
General information
Molecular weight
251.27g/mol
Molar mass
251.2590g/mol
Density
1.4960g/cm3
Appearence

2-(Trifluoromethyl)-10H-phenothiazine typically appears as a solid crystalline substance.

Comment on solubility

Solubility of 2-(trifluoromethyl)-10H-phenothiazine

2-(trifluoromethyl)-10H-phenothiazine, a compound featuring a complex aromatic structure, exhibits intriguing solubility characteristics. Solubility depends significantly on the molecule's structure, molecular weight, and polarity. In the case of this compound, consider the following factors:

  • Polarity: The presence of the trifluoromethyl group can enhance the polarity of the molecule, affecting its solubility in various solvents.
  • Solvent Compatibility: This compound tends to dissolve better in organic solvents such as dimethyl sulfoxide (DMSO) and chlorinated solvents rather than in polar protic solvents like water.
  • Temperature Effects: Generally, solubility can increase with temperature; thus, careful temperature management can enhance dissolution rates for this compound in suitable solvents.
  • Applications: Understanding the solubility is crucial for its applications in pharmaceuticals and materials science, where specific solvent interactions can concentrate efficacy.

Overall, while detailed quantitative solubility data may not be readily available for 2-(trifluoromethyl)-10H-phenothiazine, it is essential to consider these aspects:

  1. Choose the appropriate solvent based on polarity.
  2. Assess the impact of temperature on solubility.
  3. Utilize this information to guide applications across various scientific fields.

In conclusion, the solubility behavior of 2-(trifluoromethyl)-10H-phenothiazine is defined by its molecular structure and solvent interactions, making it a fascinating subject for further investigation.

Interesting facts

Interesting Facts about 2-(Trifluoromethyl)-10H-Phenothiazine

2-(Trifluoromethyl)-10H-phenothiazine is a fascinating compound known for its diverse applications and unique chemical properties. Here are some key points to explore:

  • Structure and Chemical Family: This compound belongs to the phenothiazine family, which are known for a three-ring structure containing sulfur and nitrogen atoms.
  • Trifluoromethyl Group: The presence of the trifluoromethyl group (-CF3) into its structure can significantly influence the compound's chemical behavior and increase its stability, making it useful in various settings.
  • Pharmaceutical Applications: Compounds similar to 2-(trifluoromethyl)-10H-phenothiazine are often utilized in pharmaceuticals, especially as antipsychotic medications and anti-inflammatory agents.
  • Photoresponsive Properties: This compound exhibits intriguing photophysical properties, enabling potential use in photochemical reactions and material sciences, such as in dye-sensitized solar cells.
  • Research Interest: Its distinct properties make it a subject of intense research, particularly in fields exploring new drug design and development of organic electronic materials.

As a chemical scientist, exploring this compound opens avenues for innovative discoveries, offering insights into both basic chemistry and real-world applications. As one researcher noted, "The integration of unique functional groups in organic compounds can often lead to unexpected properties and functionalities."

Overall, 2-(trifluoromethyl)-10H-phenothiazine exemplifies the exciting field of organic chemistry, where structure and functionality intersect to create a compound with rich potential.

Synonyms
2-(Trifluoromethyl)phenothiazine
92-30-8
2-(Trifluoromethyl)-10H-phenothiazine
2-Trifluoromethylphenothiazine
2-(Trifluoromethyl)-Phenothiazine
Trifluoromethylphenothiazine
10H-Phenothiazine, 2-(trifluoromethyl)-
PHENOTHIAZINE, 2-(TRIFLUOROMETHYL)-
2-Trifluoromethyl-10H-phenothiazine
EINECS 202-145-7
MFCD00005018
NSC 50438
BRN 0226580
NSC-50438
877S053KX3
DTXSID3059050
4-27-00-01352 (Beilstein Handbook Reference)
TRIFLUOROMETHYL)-10H-PHENOTHIAZINE, 2-(
SR-01000441858-2
C13H8F3NS
2-(Trifluoromethyl)-10H-phenothiazine; 2-(Trifluoromethyl)phenothiazine; NSC 50438
cid_7082
MLS003166902
SCHEMBL560225
2-trifluoromethyl phenothiazine
2-trifluoromethyl-phenothiazine
CHEMBL541018
DTXCID1048756
UNII-877S053KX3
BDBM65841
CHEBI:92925
ALBB-036523
NSC50438
CCG-44949
STK325860
AKOS001305498
AC-1827
CS-W021465
FT52329
2-(Trifluoromethyl)-10H-phenothiazine #
AS-14298
SMR001814476
SY049028
DB-019568
NS00041388
T1407
EN300-20475
O10543
SR-01000441858
SR-01000441858-1
BRD-K53032901-001-03-8
Q27164667
Z104478346
202-145-7