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Flecainide Acetate

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Identification
Molecular formula
C20H26F6N2
CAS number
54143-55-4
IUPAC name
[2-(trifluoromethyl)phenyl]methyl-[[4-[[[2-(trifluoromethyl)phenyl]methylammonio]methyl]-1-bicyclo[2.2.2]octanyl]methyl]ammonium;dichloride
State
State

In its pure form, Flecainide Acetate is typically in the solid state at room temperature.

Melting point (Celsius)
148.00
Melting point (Kelvin)
421.15
Boiling point (Celsius)
248.00
Boiling point (Kelvin)
521.15
General information
Molecular weight
474.34g/mol
Molar mass
474.3410g/mol
Density
1.2850g/cm3
Appearence

Flecainide Acetate is typically a white or nearly white crystalline powder. It is very slightly soluble in water and sparingly soluble in alcohol and in methylene chloride.

Comment on solubility

Solubility of [2-(trifluoromethyl)phenyl]methyl-[[4-[[[2-(trifluoromethyl)phenyl]methylammonio]methyl]-1-bicyclo[2.2.2]octanyl]methyl]ammonium;dichloride

The compound [2-(trifluoromethyl)phenyl]methyl-[[4-[[[2-(trifluoromethyl)phenyl]methylammonio]methyl]-1-bicyclo[2.2.2]octanyl]methyl]ammonium;dichloride exhibits unique solubility characteristics due to its complex structure. Understanding its solubility is crucial for its applications and behavior in various environments.

General Solubility Characteristics

Typically, the solubility of such quaternary ammonium compounds can be influenced by several factors:

  • Polarity: The presence of multiple trifluoromethyl groups enhances the hydrophobic character, which may lead to reduced solubility in water.
  • Ionization: As a quaternary ammonium salt, it is likely to be soluble in polar solvents like water but may have limited solubility in non-polar organic solvents.
  • Temperature: Solubility can also be temperature-dependent; generally, increasing temperature tends to improve solubility for salts in aqueous solutions.
  • pH: The pH of the solution might affect the ionization state of the compound, thus affecting its solubility. Careful consideration of the surrounding environment is vital.

Practical Implications

In practical applications, the solubility of this compound can lead to the following considerations:

  • In formulation chemistry, the solubility profile influences the choice of solvents and additives.
  • Its solubility can affect the compound's availability in biological systems, impacting pharmacological activity.
  • Understanding solubility helps in predicting the behavior in processes such as extraction, crystallization, and environmental stability.

Overall, while the compound is expected to be soluble in polar solvents, its performance and utility will hinge on a thorough understanding of these solubility parameters. As one researcher aptly put it, "A compound's solubility is often its key to revealing its true potential." This emphasizes the need for careful assessment in both laboratory and practical applications.

Interesting facts

Interesting Facts about [2-(trifluoromethyl)phenyl]methyl-[[4-[[[2-(trifluoromethyl)phenyl]methylammonio]methyl]-1-bicyclo[2.2.2]octanyl]methyl]ammonium; dichloride

This compound is quite fascinating due to its complex structure and potential applications in various fields. Here are some points to consider:

  • Structural Diversity: The compound contains a bicyclic structure, which is known for imparting unique conformational properties. Bicyclo[2.2.2]octane frameworks are less common, making this compound of particular interest in organic synthesis.
  • Fluorinated Phenyl Groups: The presence of trifluoromethyl groups in the structure can greatly enhance the lipophilicity and metabolic stability of the compound. This modification is often associated with improved biological activity, making it relevant in medicinal chemistry.
  • Ammonium Salts: The dichloride component suggests that this compound may behave as a quaternary ammonium salt. Such compounds are often used as surfactants or in drug formulation due to their ability to improve solubility and stability.
  • Potential Biological Activity: Chemical compounds that incorporate both aromatic and quaternary ammonium structures frequently exhibit interesting biological properties. This could mean potential use in pharmaceuticals or agrochemicals.
  • Research Applications: This compound may be of interest in materials science for the development of new polymers or in the area of nanotechnology due to its complex features and potential to influence surface interactions.

In summary, the intriguing combination of bicyclic structures, fluorinated groups, and quaternary ammonium characteristics makes this compound a valuable subject of study. Its multifaceted nature could pave the way for advancements in medicinal chemistry and materials science.

Synonyms
1,4-Bicyclo(2.2.2)octanebis(methylamine), N,N'-bis(2-trifluoromethylbenzyl)-, dihydrochloride
2477-23-8
N,N'-Bis(2-trifluoromethylbenzyl)-1,4-bicyclo(2.2.2)octanebis(methylamine) dihydrochloride