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2-(Trimethylsilyl)ethanol

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Identification
Molecular formula
C5H14OSi
CAS number
3277-01-4
IUPAC name
2-trimethylsilylethanol
State
State

2-(Trimethylsilyl)ethanol is a liquid at room temperature. Its low melting point and liquid state make it suitable for various applications in organic synthesis.

Melting point (Celsius)
-70.00
Melting point (Kelvin)
203.15
Boiling point (Celsius)
143.00
Boiling point (Kelvin)
416.15
General information
Molecular weight
132.30g/mol
Molar mass
132.2960g/mol
Density
0.8183g/cm3
Appearence

2-(Trimethylsilyl)ethanol appears as a colorless liquid. It generally does not have any distinctive color or particulate matter suspended within it. This lack of color is typical for many small organosilicon compounds.

Comment on solubility

Solubility of 2-trimethylsilylethanol

2-trimethylsilylethanol, with its complex structure, exhibits a distinctive solubility profile that is influenced by both its hydrophilic and hydrophobic characteristics. This compound is known to be:

  • Soluble in organic solvents: Due to its silane moiety, 2-trimethylsilylethanol tends to dissolve well in non-polar and weakly polar solvents such as hexane, chloroform, and ethyl acetate.
  • Poorly soluble in water: The presence of the silane group limits its interactions with water molecules, resulting in low solubility. It is essential to keep in mind that the solubility can further decrease with increasing temperature.

This compound's solubility characteristics can make it a unique choice in various applications within organic synthesis and material science. It is often utilized in environments where compatibility with organic phases is crucial. Thus, understanding its solubility can be key to effectively utilizing 2-trimethylsilylethanol in practical applications. As with many compounds, it's important to note that the solubility may vary depending on the specific solvent and ambient conditions.

Interesting facts

Interesting Facts about 2-Trimethylsilylethanol

2-Trimethylsilylethanol is a fascinating chemical compound that finds its application in various fields, particularly in organic chemistry and pharmaceuticals. Here are some intriguing points about this compound:

  • Structure and Functionality: This compound is characterized by the presence of a trimethylsilyl group attached to an ethanol backbone, showcasing the unique integration of silanes into organic molecules.
  • Reactivity: 2-Trimethylsilylethanol is known for its versatility in reactions. It can undergo deprotection reactions due to the trimethylsilyl group, making it useful in synthetic pathways where selective removal of protecting groups is desirable.
  • Role in Synthesis: It serves as a significant intermediate in the synthesis of complex organic compounds, particularly in the production of silicon-containing pharmaceuticals and other agrochemicals.
  • Applications: The compound is particularly valued in the field of analytical chemistry, especially in methods such as gas chromatography. Its unique properties can aid in the separation and identification of various organic compounds.
  • Safety and Handling: Like many organosilicon compounds, safety precautions must be taken as it may pose certain hazards. Proper handling and storage are essential to ensure laboratory safety.

In summation, 2-trimethylsilylethanol exemplifies how the incorporation of silicon into organic chemistry can expand the toolbox of synthetic chemists. Its versatility and functional properties continue to inspire research and development across multiple scientific disciplines.

Synonyms
2-(Trimethylsilyl)ethanol
2916-68-9
(2-Hydroxyethyl)trimethylsilane
ETHANOL, 2-(TRIMETHYLSILYL)-
Silane, (2-hydroxyethyl)trimethyl-
GF24TDM0VO
EINECS 220-844-5
NSC 96784
BRN 1732034
UNII-GF24TDM0VO
NSC-96784
Trimethyl-2-hydroxyethylsilane
2-(trimethylsilyl)ethyl alcohol
DTXSID80183421
2-(TRIMETHYLSILANYL)ETHANOL
4-04-00-03951 (Beilstein Handbook Reference)
.BETA.-(TRIMETHYLSILYL)ETHANOL
2-TMSE
DTXCID90105912
BETA-(TRIMETHYLSILYL)ETHANOL
220-844-5
inchi=1/c5h14osi/c1-7(2,3)5-4-6/h6h,4-5h2,1-3h
znginkjhqqqord-uhfffaoysa-n
2-trimethylsilylethanol
2-(trimethylsilyl)ethan-1-ol
2-HYDROXYETHYLTRIMETHYLSILANE
2-Trimethylsilanyl-ethanol
2-(trimethylsily)ethanol
2-(trimethylsilyl)-ethanol
CHEMBL25482
143591-29-1
2-(Trimethylsilanyl)ethanol; 2-(Trimethylsilyl)ethanol; 2-(Trimethylsilyl)ethyl alcohol
C5H14OSi
2-(Trimethylsilyl) ethanol
CEQ
NSC96784
MFCD00002825
TMSCH2CH2OH
2- trimethylsilylethanol
2-trimethylsilyl-ethanol
2-trimethylsilanylethanol
SCHEMBL151
2-(Trimethylsilyl)ethanol, 99%
STR05012
WLN: Q2-SI-1&1&1
BDBM50026469
AKOS015840137
FT33997
PB47630
s19375
DB-009475
CS-0015144
NS00049633
T1441
EN300-67241
(2-Hydroxyethyl)trimethylsilane; 2-(Trimethylsilanyl)ethanol; 2-(Trimethylsilyl)ethyl Alcohol; NSC 96784; beta-(Trimethylsilyl)ethanol